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A Minimal Physiologically Based Pharmacokinetic Model with a Nested Endosome Compartment for Novel Engineered

Dongfen Yuan1, Frederik Rode2, Yanguang Cao3,4

  • 1Division of Pharmacotherapy and Experimental Therapeutics, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, 301 Pharmacy Lane, Chapel Hill, North Carolina, 27599, USA.

The AAPS Journal
|March 16, 2018
PubMed

Keywords:
FcRnendosomemPBPK modelpharmacokineticsrecycling antibody

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