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Surgery and Sample Processing for Correlative Imaging of the Murine Pulmonary Valve
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Feasibility of surgery for pulmonary aspergilloma: analysis of the operative modes

Kazuyuki Komori1, Aritoshi Hattori1, Takeshi Matsunaga1

  • 1Department of General Thoracic Surgery, Juntendo University School of Medicine, 1-3, Hongo 3-chome, Bunkyo-ku, Tokyo, 113-8431, Japan.

General Thoracic and Cardiovascular Surgery
|March 16, 2018
PubMed
Abstract

Insights

Surgery for pulmonary aspergilloma is feasible with acceptable morbidity. Preoperative artery embolization (PAE) may reduce surgical stress, though it was associated with increased adhesions. Outcomes were favorable in this study.

Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Infectious Diseases

Background:

  • Pulmonary aspergilloma, a fungal infection in the lungs, poses surgical challenges.
  • Surgical intervention is a key treatment modality for symptomatic pulmonary aspergilloma.
  • Evaluating surgical feasibility and outcomes is crucial for patient management.

Purpose of the Study:

  • To assess the feasibility and outcomes of surgical resection for pulmonary aspergilloma.
  • To compare perioperative morbidity based on different surgical approaches.
  • To evaluate the impact of preoperative artery embolization (PAE) on surgical stress.

Main Methods:

  • Retrospective analysis of 35 patients undergoing surgery for pulmonary aspergilloma.
  • Comparison of clinical characteristics and surgical morbidity across operative modes.
  • Selective use of PAE to mitigate intraoperative blood loss and surgical stress.

Main Results:

  • The study included 35 patients (19 males, 16 females; mean age 56 years).
  • Lobectomy was the most common procedure (n=22), followed by segmentectomy (n=5), wedge resection (n=4), and palliative surgery (n=4).
  • Postoperative morbidity occurred in 34% of patients, with no life-threatening complications or infection recurrence. PAE was performed in 26% of cases and was linked to increased intrathoracic adhesions but not significantly different operative times or blood loss. No 30-day mortality was observed with a median follow-up of 41.5 months.

Conclusions:

  • Surgical management of pulmonary aspergilloma is feasible with acceptable postoperative morbidity.
  • Preoperative artery embolization (PAE) appears effective in reducing surgical stress.
  • Pulmonary aspergilloma surgery demonstrates favorable long-term outcomes.
Keywords:
OutcomePreoperative artery embolizationPulmonary aspergillomaSurgical resection

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