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A Detailed Protocol for Physiological Parameters Acquisition and Analysis in Neurosurgical Critical Patients
Published on: October 17, 2017
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Esthesioneuroblastoma : neurosurgical implications
B S Sharma1, V K Gupta1, V K Khosla1
1Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh - 160 012, India.
Neurology India
|March 16, 2018
Summary
This study reports on six esthesioneuroblastoma cases, detailing varied presentations from nasal to intracranial. Aggressive multimodal treatment, including chemotherapy, improved quality of life for patients with recurrent or metastatic disease.
Area of Science:
- Oncology
- Neurosurgery
- Radiology
Background:
- Esthesioneuroblastoma is a rare malignant tumor arising from the olfactory epithelium.
- Tumor presentation varies, including nasal, intracranial, or mixed involvement.
- Understanding treatment outcomes for different esthesioneuroblastoma presentations is crucial.
Purpose of the Study:
- To report on six histologically confirmed cases of esthesioneuroblastoma.
- To analyze the clinical presentations, treatment strategies, and outcomes.
- To discuss the role of CT imaging and chemotherapy in managing esthesioneuroblastoma.
Main Methods:
- Retrospective review of six histologically confirmed esthesioneuroblastoma cases.
- Analysis of clinical data, including tumor presentation, treatment modalities (surgery, radiation, chemotherapy), and follow-up.
- Review of CT scan findings.
Main Results:
- Presentations included primary intracranial mass (2 cases), intracranial extension of nasal tumor (2 cases), and isolated nasal growth (2 cases).
- Local recurrence and distant metastases (vertebra, extradural, subarachnoid space) were observed.
- Aggressive treatment combining surgery, radiation, and chemotherapy improved quality of life in recurrent and metastatic cases.
Conclusions:
- Esthesioneuroblastoma exhibits diverse clinical presentations requiring tailored treatment approaches.
- Multimodal aggressive therapy, including chemotherapy, is effective in managing locally recurrent and metastatic disease.
- CT imaging plays a vital role in diagnosis and treatment planning for esthesioneuroblastoma.
