Related Experiment Video
Updated: Feb 13, 2026

Extraction of Histones from Clinical Specimens for Epigenetic Profiling by Mass Spectrometry
Published on: November 21, 2025
Polymyositis : a clinical profile
A Thussu1, S Prabhakar1, S K Bansal1
1Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh - 160012, India.
Abstract:
Clinical data of 132 patients of polymyositis seen over a period of ten years was retrospectively analysed. Important features included a mean age of 32.31 years with a range of 8 years to 70 years. 40.62 percent patients were of primary idiopathic polymyositis while 53.13 percent presented with disease of more than six months duration. Pelvic girdle weakness was demonstrated in 31 cases (96.87 percent). Creatin phosphokinase (CPK) values were consistently elevated in 81.25 percent of these cases. Electromyography in majority showed mixed neurogenic and myopathic pattern. Muscle biopsy was performed in 23 patients and all revealed changes characteristic of polymyositis. Follow up was available in 18 cases.
Related Concept Videos
Ribosome Profiling
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
Nursing Clinical Information System
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Taping Over Different Ground Profiles
Toxidromes: Clinical Features

