Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

645
Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
645
What are Lipids?01:38

What are Lipids?

221.2K
Overview
221.2K
What are Lipids?01:31

What are Lipids?

11.4K
Lipids function as structural components of cellular membranes, in addition to acting as energy reservoirs and signaling molecules. They are thus crucial to all living organisms.  The three biologically important classes of lipids are triglycerides, phospholipids, and steroids.
Non-Polar and Hydrophobic Characteristics of Lipids
Lipids are a structurally and functionally diverse group of hydrocarbons—compounds consisting of carbon and hydrogen atoms. The carbon-carbon and...
11.4K
Lipid Digestion01:06

Lipid Digestion

99.8K
Lipids are large molecules that are generally not water-soluble. Since most of the digestive enzymes in the human body are water-based, there are specific steps the body must take to break down lipids and make them available for use.
99.8K
Structure of Lipids03:38

Structure of Lipids

99.2K
Lipids include a diverse group of compounds that are largely nonpolar in nature. This is because they are hydrocarbons that include mostly nonpolar carbon-carbon or carbon-hydrogen bonds. Non-polar molecules are hydrophobic (“water fearing”), or insoluble in water. Lipids perform many different functions in a cell. Cells store energy for long-term use in the form of fats. Lipids also provide insulation from the environment for plants and animals. For example, they help keep aquatic...
99.2K
Lipids as Anchors01:32

Lipids as Anchors

7.4K
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
7.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A case-control study on QEEG as a marker of cognition in depression.

Indian journal of psychiatry·2025
Same author

Complications Encountered with ETV in Infants with Congenital Hydrocephalus.

Neurology India·2022
Same author

Polymorphisms in vitamin D receptor, toll-like receptor 2 and Toll-Like receptor 4 genes links with Dengue susceptibility.

Bioinformation·2021
Same author

Expeditious quest for the best vaccine: the game is on.

QJM : monthly journal of the Association of Physicians·2021
Same author

Cardiovascular complications and its relationship with functional outcomes in Guillain-Barré syndrome.

QJM : monthly journal of the Association of Physicians·2019
Same author

Sample attrition rate of a community study: An analysis of Lucknow urban and rural elderly follow-up over a period of 9 years.

Indian journal of psychiatry·2019
Same journal

A Life in Service of Neuroscience, Healing, and Teaching.

Neurology India·2026
Same journal

IN MEMORIAM.

Neurology India·2026
Same journal

Extensive Diffusion Restriction of White Matter, Midbrain, and Basal ganglia in a Neonate with Refractory Hypoglycemic Seizures.

Neurology India·2026
Same journal

CHD2-Related Developmental Epileptic Encephalopathy and Angelman Syndrome in a Girl: A Double Jeopardy.

Neurology India·2026
Same journal

Cerebral Schistosomiasis Mimicking Multiple Intracranial Metastases.

Neurology India·2026
Same journal

Extrusion of Spinal Implants Through the Overlying Skin: A Rare Epiphenomenon of Metal Allergy.

Neurology India·2026
See all related articles

Related Experiment Video

Updated: Feb 13, 2026

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
10:45

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies

Published on: February 7, 2025

1.6K

Serum lipids and stroke.

A M Kar1, R K Garg1, Sps Gaur1

  • 1Department of Neurology, King George's Medical College, Lucknow, India.

Neurology India
|March 16, 2018
PubMed
Summary
This summary is machine-generated.

Serum lipid levels, particularly low-density lipoprotein (LDL) and high-density lipoprotein (HDL), are linked to cerebrovascular atherosclerosis. Optimal timing for post-stroke lipid testing remains unclear, impacting risk assessment.

More Related Videos

Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis
06:07

Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis

Published on: May 6, 2021

7.8K
Determination of Total Lipid and Lipid Classes in Marine Samples
14:59

Determination of Total Lipid and Lipid Classes in Marine Samples

Published on: December 11, 2021

5.3K

Related Experiment Videos

Last Updated: Feb 13, 2026

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies
10:45

The Mouse Stroke Unit Protocol with Standardized Neurological Scoring for Translational Mouse Stroke Studies

Published on: February 7, 2025

1.6K
Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis
06:07

Modeling Stroke in Mice: Focal Cortical Lesions by Photothrombosis

Published on: May 6, 2021

7.8K
Determination of Total Lipid and Lipid Classes in Marine Samples
14:59

Determination of Total Lipid and Lipid Classes in Marine Samples

Published on: December 11, 2021

5.3K

Area of Science:

  • Cardiovascular Science
  • Neurology
  • Metabolic Disorders

Background:

  • Serum lipids and lipoproteins are established risk factors for coronary atherosclerosis.
  • Their association with cerebrovascular atherosclerosis, including carotid artery disease, is less consistent but increasingly recognized.
  • Specific lipid profiles, such as elevated low-density lipoprotein (LDL) and reduced high-density lipoprotein (HDL), correlate with atherosclerosis.

Purpose of the Study:

  • To explore the relationship between serum lipids and lipoproteins and cerebrovascular atherosclerosis.
  • To evaluate the utility of various lipid markers in assessing cranial atherosclerosis.
  • To discuss the implications of cholesterol levels on stroke pathology and the challenges in post-stroke lipid assessment.

Main Methods:

  • Review of existing studies correlating lipid levels with angiographic or ultrasonographic evidence of carotid artery atherosclerosis.
  • Analysis of the role of conventional lipids, advanced lipoprotein markers (e.g., Lipoprotein (a), Apo B, Apo AI), and HDL subfractions.
  • Discussion of the impact of total serum cholesterol levels on different stroke types (hemorrhage vs. atherothrombosis).

Main Results:

  • Increased LDL and decreased HDL show a correlation with carotid artery atherosclerosis.
  • Lipoprotein (a), apolipoproteins, and HDL subfractions may be superior indicators of cranial atherosclerosis compared to standard lipid panels.
  • Cholesterol levels influence stroke type: low levels (<160 mg/dL) are linked to intracerebral hemorrhage, while high levels predispose to large vessel atherothrombosis.

Conclusions:

  • While lipid profiles are linked to cerebrovascular disease, precise risk prediction and the impact of lipid-lowering interventions on stroke incidence require further investigation.
  • The optimal timing for serum lipid and lipoprotein analysis following a stroke is not definitively established, with differing opinions on immediate versus delayed testing.
  • Management of hyperlipidemia is crucial for reducing the risk of coronary heart disease and potentially subsequent strokes.