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Sensory ataxic neuropathy with axonal stasis in a case of primary polycythemia : electrophysiological and
A B Taly1, S K Shankar1, D Nagaraja1
1Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore - 560 029, India.
Abstract:
A case of chronic sensory ataxic neuropathy secondary to primary polycythemia is reported. This association, has not been recorded before. Electrophysiological investigations revealed features consistent with severe sensory and mild motor axonopathy. Sural nerve biopsy showed severe fibre loss and Schwann cell proliferation. Ultra structurally accumulation of neurofilaments was noted in both unmyelinated and myelinated fibres. Low persistent ischaemia of nerves due to hyperviscosity is the probablepathogenic mechanism for the axonal stasis and nerve damage.
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