[Allergic contact eczema caused by trifluorothymidine]

Over the past years pyrimidine analogues have gained an important role within the concept of local therapy of viral infections, in particular in the field of ophthalmology. This report deals with a case of contact allergy to trifluorothymidine in a 15 year-old atopic patient. Since until now only a small number of contact allergic reactions have been reported, the halogenated pyrimidine analogues seem to be weak sensitizers. Cross reactivity within these substances may occur.