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Updated: Feb 13, 2026
03:57
Electrochemotherapy of Tumours
Published on: December 15, 2008
25.1K
Unusual case of a rectal tumour
Maryam Alfa-Wali1, Samantha Muktar2, Dimitrios Pissas3
1Imperial College London, London, UK.
BMJ Case Reports
|March 17, 2018
Summary
A rectal mass initially suspected as colorectal cancer was diagnosed as lymphogranuloma venereum in an HIV-positive patient. Treatment with doxycycline resolved the condition, underscoring the need for HIV testing in similar cases.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Oncology
Background:
- A 48-year-old male presented with rectal bleeding, initially suspected as colorectal cancer.
- Imaging revealed a locally infiltrative mid-lower rectal tumor, staged T3d/T4 N2 MX.
Observation:
- Colonoscopy showed severe proctitis, but biopsies were negative for malignancy.
- The patient tested positive for human immunodeficiency virus (HIV).
- Rectal swab testing confirmed *Chlamydia trachomatis* serovar L2, indicating lymphogranuloma venereum (LGV).
Findings:
- The patient received doxycycline treatment for LGV.
- Subsequent MRI scans demonstrated a reduction in tumor size, with eventual resolution.
- Repeat biopsies confirmed the absence of malignancy.
Implications:
- This case highlights the importance of considering and testing for HIV in patients presenting with colorectal tumors.
- LGV should be considered in the differential diagnosis of rectal masses, especially in HIV-positive individuals.
- Prompt diagnosis and treatment of LGV can lead to resolution of rectal symptoms and masses.
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