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Related Concept Videos

Coordination Number and Geometry02:57

Coordination Number and Geometry

19.1K
For transition metal complexes, the coordination number determines the geometry around the central metal ion. Table 1 compares coordination numbers to molecular geometry. The most common structures of the complexes in coordination compounds are octahedral, tetrahedral, and square planar.
19.1K
Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

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The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
12.2K
Coordination Compounds and Nomenclature02:54

Coordination Compounds and Nomenclature

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In most main group element compounds, the valence electrons of the isolated atoms combine to form chemical bonds that satisfy the octet rule. For instance, the four valence electrons of carbon overlap with electrons from four hydrogen atoms to form CH4. The one valence electron leaves sodium and adds to the seven valence electrons of chlorine to form the ionic formula unit NaCl (Figure 1a). Transition metals do not normally bond in this fashion. They primarily form coordinate covalent bonds, a...
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Analysis of Population Pharmacokinetic Data01:12

Analysis of Population Pharmacokinetic Data

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Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
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Equations of Motion: Rectangular Coordinates and Cylindrical Coordinates01:21

Equations of Motion: Rectangular Coordinates and Cylindrical Coordinates

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Understanding the motion of particles is a fundamental aspect of classical mechanics, and the choice of the coordinate system plays a pivotal role in unraveling the complexities of their dynamics.
When a particle moves relative to an inertial frame, the equations of motion can be expressed using rectangular components. If the motion is confined to the x-y plane, the equations having the x and y coordinates only can be used to simplify the mathematical representation.
However, when particles...
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Directing Effect of Substituents: meta-Directing Groups01:09

Directing Effect of Substituents: meta-Directing Groups

6.0K
Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
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Related Experiment Video

Updated: Feb 13, 2026

Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI
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Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI

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The coordinate-based meta-analysis of neuroimaging data.

Pantelis Samartsidis1, Silvia Montagna2, Thomas E Nichols3

  • 1MRC Biostatistics Unit, University Forvie Site, Robinson Way, Cambridge CB2 0SR, UK.

Statistical Science : a Review Journal of the Institute of Mathematical Statistics
|March 17, 2018
PubMed
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Neuroimaging meta-analysis methods are evolving due to unique data characteristics. This review covers existing techniques, their pros and cons, and future research directions in statistical neuroimaging.

Keywords:
functional magnetic resonance imagingmeta-analysisneuroimaging

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Area of Science:

  • Statistical analysis applied to neuroscience.
  • Advanced neuroimaging data interpretation.

Background:

  • Neuroimaging meta-analysis is a rapidly developing statistical field.
  • Traditional meta-analysis techniques are unsuitable for neuroimaging data.

Purpose of the Study:

  • To review current neuroimaging meta-analysis methodologies.
  • To evaluate the advantages and disadvantages of existing methods.
  • To identify open challenges and guide future research.

Main Methods:

  • Review of statistical techniques for neuroimaging meta-analysis.
  • Demonstration using a real-world dataset from emotion studies.
  • Comparative analysis of different methodologies.

Main Results:

  • Existing neuroimaging meta-analysis methods have specific benefits and drawbacks.
  • A practical application highlights the nuances of applying these methods.
  • The study underscores the need for further methodological development.

Conclusions:

  • Novel statistical approaches are essential for neuroimaging meta-analysis.
  • Further research is required to address current limitations.
  • The field shows significant potential for advancing neuroscience.