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BURRITO: An Interactive Multi-Omic Tool for Visualizing Taxa-Function Relationships in Microbiome Data.

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Summary
This summary is machine-generated.

A new web tool, BURRITO, visualizes microbiome data, linking taxonomic and gene composition. It helps researchers explore the co-variation between microbial taxa and their functions for better understanding complex microbiomes.

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Area of Science:

  • Microbiology
  • Bioinformatics
  • Computational Biology

Background:

  • Microbiome research increasingly relies on sequencing technologies to assay taxonomic and gene abundance.
  • Existing software tools effectively visualize taxonomic or functional data separately.
  • A gap exists in tools that visualize the integrated relationship between microbiome taxonomic and functional composition.

Purpose of the Study:

  • To introduce BURRITO, a novel web tool for interactive visualization of microbiome multi-omic data.
  • To enable simultaneous visualization of taxonomic and functional compositions across multiple samples.
  • To facilitate exploratory analysis of the co-variation between microbial taxa and gene content.

Main Methods:

  • BURRITO is a web-based tool for interactive visualization.
  • It integrates paired taxonomic and functional microbiome data.
  • The tool allows users to explore relationships between taxa and functions, adjust data granularity, and export figures.

Main Results:

  • BURRITO simultaneously visualizes taxonomic and functional microbiome data.
  • It dynamically highlights relationships between specific taxa and functions.
  • Users can interactively explore the contribution of each taxon to overall functions across samples.

Conclusions:

  • BURRITO addresses the lack of integrated visualization tools for microbiome multi-omic data.
  • The tool facilitates a deeper understanding of the interplay between microbiome structure and function.
  • It provides a valuable resource for analyzing complex microbiome datasets and generating publication-ready figures.