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RE: 'Streptococcus pluranimalium: A novel human pathogen?'
Peter Pongratz1, Meinolf Ebbers1, Hilte Geerdes-Fenge1
1Rostock University Medical Center, Division of Tropical Medicine and Infectious Diseases, Ernst-Heydemann-Strasse 6, 18057 Rostock, Germany.
International Journal of Surgery Case Reports
|March 17, 2018
Summary
Streptococcus pluranimalium is not conclusively proven as a human pathogen. Advanced techniques like MALDI-TOF and 16S rRNA analysis have failed to confirm human infections, despite previous Vitek2 reports.
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Diagnostics
Background:
- Streptococcus pluranimalium has been suggested as a novel human pathogen.
- Previous human cases were identified using the Vitek2 system.
- Nonhemolytic streptococci require precise identification methods.
Purpose of the Study:
- To evaluate the conclusive evidence for Streptococcus pluranimalium as a human pathogen.
- To assess the efficacy of advanced diagnostic techniques in identifying this bacterium in humans.
Main Methods:
- Review of reported human cases.
- Analysis of identification techniques including Vitek2, MALDI-TOF, and 16S rRNA gene sequencing.
- Assessment of strain discrimination capabilities for highly conserved genes.
Main Results:
- Despite using advanced methods like MALDI-TOF and 16S rRNA analysis, Streptococcus pluranimalium could not be definitively identified in human samples.
- No conclusive evidence was found to support human infection by Streptococcus pluranimalium.
Conclusions:
- Current advanced diagnostic techniques lack the definitive power to confirm Streptococcus pluranimalium in human infections.
- There is no conclusive evidence to support Streptococcus pluranimalium as a recognized human pathogen at present.