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Surgical treatment for rebleeding caused by bypass failure after Rex shunt: re-Rex shunt or Warren shunt?
Jin-Shan Zhang1, Long Li2,3, Wei Cheng4,5
1Department of General Surgery, Capital institute of Pediatrics, Beijing, People's Republic of China.
Insights
Warren shunt is a superior surgical option for treating rebleeding after Rex shunt in children with extrahepatic portal venous obstruction (EHPVO). This approach offers better bypass vein patency and reduced rebleeding rates compared to re-Rex shunt.
Area of Science:
- Pediatric Surgery
- Vascular Surgery
- Gastroenterology
Background:
- Extrahepatic portal venous obstruction (EHPVO) is a serious condition in children, often treated with Rex shunt.
- Rebleeding occurs in 4-20% of children post-Rex shunt due to graft complications.
- Surgical management of rebleeding after Rex shunt requires careful consideration of alternative procedures.
Purpose of the Study:
- To evaluate the effectiveness of surgical treatments for rebleeding following Rex shunt in pediatric patients.
- To compare re-Rex shunt with Warren shunt for managing bypass failure after initial Rex shunt.
Main Methods:
- A retrospective review of 12 children with EHPVO who underwent a second operation between June 2008 and January 2017.
- Diagnosis of bypass vein issues (occlusion/stenosis) confirmed by ultrasound and CT.
- Surgical interventions included re-Rex shunt (n=8) and Warren shunt (n=5), with one re-Rex converted to Warren shunt.
Main Results:
- Warren shunt demonstrated significantly lower postoperative rebleeding and esophageal varices incidence compared to re-Rex shunt (P=0.027 and 0.015).
- Bypass vein patency rates were higher with Warren shunt (100%) versus re-Rex shunt (50%) after the second operation.
- Children undergoing Warren shunt experienced significantly greater spleen size reduction postoperatively (P<0.05).
Conclusions:
- Warren shunt is a more effective treatment for pediatric rebleeding secondary to bypass failure after Rex shunt.
- The improved outcomes with Warren shunt include better graft patency and reduced clinical complications.
- This study highlights the advantages of Warren shunt in complex EHPVO management requiring revision surgery.
Purpose:
Although Rex shunt is an effective treatment for extrahepatic portal venous obstruction (EHPVO), 4-20% children develop rebleeding postoperatively. This study was used to evaluate the surgical treatment of rebleeding after Rex shunt in our center.
Method:
From June 2008 to Jan 2017, 12 of 122 children with EHPVO underwent a second operation due to graft stenosis and occlusion after Rex shunt in our center. The abdominal ultrasound and computed tomography (CT) showed the occlusion of bypass vein in nine children, stenosis of bypass vein in two children, and the patency of bypass vein in one child with dysplasia of intrahepatic portal vein. A re-Rex shunt was performed in eight children, of which one child required conversion to Warren shunt due to postoperative rebleeding. Five children underwent Warren shunt due to a narrowed left portal vein shown by intraoperative portal angiography and surgical exploration. All patients were followed up in this study.
Results:
The postoperative incidences of re-bleeding and esophageal varices in children with Warren shunt were significantly lower than those in children undergoing re-Rex shunt (P = 0.027 and 0.015). After a second operation, the rate of bypass vein patency in children with re-Rex shunt was lower than that in children with Warren shunt (50 vs. 100%). The postoperative reduced size of spleen in children undergoing Warren shunt was significantly higher than that of children undergoing re-Rex shunt (P < 0.05).
Conclusions:
Comparing to re-Rex shunt, Warren shunt was a better treatment for rebleeding caused by bypass failure after Rex shunt.
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