Surgical treatment for rebleeding caused by bypass failure after Rex shunt: re-Rex shunt or Warren shunt?

Jin-Shan Zhang1, Long Li2,3, Wei Cheng4,5

  • 1Department of General Surgery, Capital institute of Pediatrics, Beijing, People's Republic of China.

Insights

Warren shunt is a superior surgical option for treating rebleeding after Rex shunt in children with extrahepatic portal venous obstruction (EHPVO). This approach offers better bypass vein patency and reduced rebleeding rates compared to re-Rex shunt.

Area of Science:

  • Pediatric Surgery
  • Vascular Surgery
  • Gastroenterology

Background:

  • Extrahepatic portal venous obstruction (EHPVO) is a serious condition in children, often treated with Rex shunt.
  • Rebleeding occurs in 4-20% of children post-Rex shunt due to graft complications.
  • Surgical management of rebleeding after Rex shunt requires careful consideration of alternative procedures.

Purpose of the Study:

  • To evaluate the effectiveness of surgical treatments for rebleeding following Rex shunt in pediatric patients.
  • To compare re-Rex shunt with Warren shunt for managing bypass failure after initial Rex shunt.

Main Methods:

  • A retrospective review of 12 children with EHPVO who underwent a second operation between June 2008 and January 2017.
  • Diagnosis of bypass vein issues (occlusion/stenosis) confirmed by ultrasound and CT.
  • Surgical interventions included re-Rex shunt (n=8) and Warren shunt (n=5), with one re-Rex converted to Warren shunt.

Main Results:

  • Warren shunt demonstrated significantly lower postoperative rebleeding and esophageal varices incidence compared to re-Rex shunt (P=0.027 and 0.015).
  • Bypass vein patency rates were higher with Warren shunt (100%) versus re-Rex shunt (50%) after the second operation.
  • Children undergoing Warren shunt experienced significantly greater spleen size reduction postoperatively (P<0.05).

Conclusions:

  • Warren shunt is a more effective treatment for pediatric rebleeding secondary to bypass failure after Rex shunt.
  • The improved outcomes with Warren shunt include better graft patency and reduced clinical complications.
  • This study highlights the advantages of Warren shunt in complex EHPVO management requiring revision surgery.
Abstract

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