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Plate-Based Phenotypic Screening for Pain Using Human iPSC-Derived Sensory Neurons

Peter Stacey1, Anne Mai Wassermann2, Laura Kammonen1

  • 11 Pfizer Neusentis, Great Abington, Cambridgeshire, UK.

SLAS Discovery : Advancing Life Sciences R & D
|March 17, 2018
PubMed
Summary

This study developed a high-throughput screening method using human induced pluripotent stem cell-derived sensory neurons to identify pain-modulating compounds. The novel assay enables robust phenotypic screening for neuronal excitability, advancing pain research.

Keywords:
cell-based assaysiPSCneuronsphenotypic drug discoverystem cells

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