RETINAL MICROSTRUCTURE IN POEMS SYNDROME
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Updated: Feb 13, 2026

Ultrasonic Assessment of Myocardial Microstructure
Published on: January 14, 2014
Ryutaro Tomita1, Tetsuju Sekiryu1, Hiroaki Shintake2
1Department of Ophthalmology, Fukushima Medical University School of Medicine, Fukushima, Japan; and.
Purpose:
To report a 67-year-old woman with polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome, showing bilateral serous retinal detachment. The retinal lesion was evaluated by multimodal imaging using spectral domain optical coherence tomography and an adaptive optics (AO) camera.
Methods:
A case report.
Results:
Optical coherence tomography showed hyperreflective foci mainly in the inner retina in both eyes. The AO images showed many low-reflective dots in the right eye. Three months after hematological treatment, both hyperreflective foci in the optical coherence tomography images and the low-reflective dots in the AO images disappeared.
Conclusion:
Low-reflective dots were detected in AO images of eyes with serous retinal detachment secondary to POEMS syndrome. AO cameras can detect retinal microstructures in living eyes.
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