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Related Concept Videos

Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

277
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
277
Pharmacokinetics in Pediatric Patients: Drug Distribution01:17

Pharmacokinetics in Pediatric Patients: Drug Distribution

334
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
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Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

246
In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
246
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption01:23

Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

310
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
310

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Ambulatory ECG Recording in Mice
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Ambulatory pediatric surgery.

Andrew B Nordin1, Sohail R Shah2, Brian D Kenney3

  • 1Nationwide Children's Hospital, Department of Pediatric Surgery, 700 Children's Drive, Columbus, OH 43205, United States; State University of New York University at Buffalo, Department of General Surgery, 100 High St, Buffalo, NY 14203, United States.

Seminars in Pediatric Surgery
|March 18, 2018
PubMed
Summary
This summary is machine-generated.

Ambulatory pediatric surgery is growing, offering benefits for hospitals and families. Careful patient selection and anesthetic choices are key to maximizing outpatient surgery opportunities.

Keywords:
Day surgeryEfficientTelephone followupTurnover

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Area of Science:

  • Pediatric surgery
  • Outpatient healthcare services

Background:

  • Ambulatory pediatric surgery is increasingly prevalent.
  • Outpatient procedures offer advantages for healthcare systems and patients.

Purpose of the Study:

  • To highlight the growing trend of ambulatory pediatric surgery.
  • To emphasize critical factors for successful outpatient pediatric procedures.

Main Methods:

  • Review of current trends in pediatric outpatient surgery.
  • Analysis of patient and procedure selection criteria.
  • Consideration of anesthetic techniques for ambulatory settings.

Main Results:

  • Increased utilization of outpatient settings for pediatric surgical cases.
  • Identification of key factors influencing the success of ambulatory pediatric surgery.
  • Potential for single-visit procedures to streamline care.

Conclusions:

  • Optimizing ambulatory pediatric surgery requires careful patient and procedure selection.
  • Anesthetic management is crucial for same-day surgical discharge.
  • Further development of single-visit procedures can enhance efficiency and patient satisfaction.