Related Experiment Video

Updated: Feb 13, 2026

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
14:19

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

12.1K

Clinical outcomes after acute myocardial infarction according to a novel stratification system linked to a

Kei Yamamoto1, Kenichi Sakakura1, Naoyuki Akashi1

  • 1Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.

Journal of Cardiology
|March 18, 2018
PubMed

Insights

A new risk classification for acute myocardial infarction (AMI) patients in cardiac rehabilitation shows significant differences in hospital stay and major adverse cardiac events (MACE) across low, intermediate, and high-risk groups.

Area of Science:

  • Cardiology
  • Clinical Research
  • Rehabilitation Medicine

Background:

  • Establishing a risk classification for acute myocardial infarction (AMI) patients undergoing cardiac rehabilitation is crucial.
  • Previous risk stratification models for AMI rehabilitation have not been widely established.

Purpose of the Study:

  • To introduce and validate a novel risk classification system for patients with acute myocardial infarction (AMI).
  • To assess the correlation between risk groups and clinical outcomes, including hospital stay duration and major adverse cardiac events (MACE).

Main Methods:

  • 292 AMI patients were categorized into low (L), intermediate (I), and high (H) risk groups.
  • The primary endpoint was major adverse cardiac events (MACE): cardiac death, non-fatal AMI, stent thrombosis, and ischemia-driven target vessel revascularization.
  • Follow-up was conducted for a mean period of 252 days.

Main Results:

  • Coronary care unit (CCU) and hospital stays were shortest in the L-risk group and longest in the H-risk group (p<0.001).
  • Major adverse cardiac events (MACE) incidence was significantly higher in the H-risk group (26.8%) compared to the I-risk (5.6%) and L-risk (1.9%) groups (p<0.001).

Conclusions:

  • The developed risk classification system effectively differentiates AMI patients based on hospital stay duration.
  • The system demonstrates significant correlations with major adverse cardiac events (MACE), supporting its clinical validity for cardiac rehabilitation programs.
Abstract

Keywords:
Acute myocardial infarctionMajor adverse cardiac eventRisk stratification

More Related Videos

Acute Myocardial Infarction in Rats07:45

Acute Myocardial Infarction in Rats

Published on: February 16, 2011

54.7K
Myocardial Infarction and Functional Outcome Assessment in Pigs12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.7K

Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
891
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
448
Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
984
Covalently Linked Protein Regulators02:04

Covalently Linked Protein Regulators

Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
9.7K
Predicting Reaction Outcomes02:24

Predicting Reaction Outcomes

Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
11.0K
Outcomes of Glycolysis01:13

Outcomes of Glycolysis

Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
107.7K