Related Experiment Video
Updated: Feb 13, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
ZipFix Versus Conventional Sternal Closure: One-Year Follow-Up
Pouya Nezafati1, Ali Shomali2, Mahdi Kahrom3
1Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
The sternal ZipFix implant significantly reduces postoperative pain and sternal dehiscence compared to conventional steel wires after cardiac surgery. This new method offers improved patient recovery and fewer complications.
Area of Science:
- Cardiovascular Surgery
- Biomaterials Science
- Surgical Innovation
Background:
- Sternotomy closure is a critical step in cardiac surgery.
- Conventional steel wire closure is associated with postoperative complications.
- Newer closure devices aim to improve outcomes.
Purpose of the Study:
- To compare postoperative complications between sternal ZipFix and conventional steel wire closure.
- To evaluate pain severity, sternal dehiscence, and infection rates.
Main Methods:
- A randomized controlled trial involving 326 cardiac surgery patients.
- Sternal closure assigned to either sternal ZipFix (n=168) or conventional wires (n=158).
- Postoperative follow-up for 12 months, assessing pain, dehiscence, and infection.
Main Results:
- No significant difference in baseline characteristics between groups.
- Significantly lower mean pain severity scores with sternal ZipFix (p<0.001).
- Sternal ZipFix showed no dehiscence, while conventional wires had 5 cases at 1 month (p<0.001).
- Infection rates were similar between groups (2.76% overall).
Conclusions:
- Sternal ZipFix offers significant clinical advantages over conventional steel wire for sternotomy closure.
- Reduced pain and sternal dehiscence are key benefits of the ZipFix implant.
- The ZipFix device represents a promising advancement in cardiac surgical closure techniques.
More Related Videos
Related Concept Videos
Sign Convention
The normal force acts perpendicular to the beam's cross-section and can...
Enolate Mechanism Conventions
Angle Closure Glaucoma: Treatment
Dose Response Curve: Conventional Versus Nonmonotonic
Molecular Models
Statistical Significance

