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08:21
Utilizing a 3D Printed Laparoscopic Nissen Fundoplication Model to Shorten a Resident's Learning Curve
Published on: August 15, 2025
739
A modified Nissen fundoplication: subjective and objective midterm results
Sabrina Rampado1, Edoardo Savarino2, Angelica Ganss3
1Department of Surgical Oncology and Gastroenterology, General Surgery, School of Medicine, University of Padova, Via Giustiniani, 2, 35128, Padova, Italy. sabrina.rampado@gmail.com.
Langenbeck'S Archives of Surgery
|March 18, 2018
Summary
Modified Nissen fundoplication (MNF) shows significant midterm success in improving reflux symptoms and quality of life. This surgical technique is safe and effective, reducing esophageal acid exposure and improving lower esophageal sphincter function.
Area of Science:
- Gastroenterology
- Surgical Innovation
- Reflux Management
Background:
- Laparoscopic anti-reflux surgery has a notable failure rate of 10-20%.
- Gastroesophageal reflux disease (GERD) significantly impacts patient quality of life.
- There is a need for improved surgical techniques to address GERD effectively.
Purpose of the Study:
- To evaluate the efficacy of a modified Nissen fundoplication (MNF) in improving GERD symptoms.
- To assess the midterm success rate of MNF in preventing surgical treatment failure.
- To investigate the impact of MNF on objective reflux parameters and esophageal function.
Main Methods:
- A prospective study involving 48 consecutive GERD patients.
- MNF procedure included esophageal suturing to diaphragmatic crura, potential mesh reinforcement, and valve fixation.
- Pre- and post-operative assessments used validated questionnaires (GERD-HRQL), high-resolution manometry, 24-h impedance-pH monitoring, endoscopy, and barium swallow.
Main Results:
- No mortality or perioperative complications were observed.
- Significant improvements in GERD symptoms and quality of life scores at a median follow-up of 46.7 months.
- Postoperative reduction in esophageal acid exposure, reflux episodes, and symptom-reflux association.
- Improvement in esophagogastric junction contractile integral (EGJ-CI) and lower esophageal sphincter (LES) abdominal length.
Conclusions:
- Modified Nissen fundoplication (MNF) is a safe procedure with no mortality or major complications.
- MNF demonstrates significant midterm effectiveness in alleviating GERD symptoms and improving patient quality of life.
- The procedure successfully reduces objective measures of acid reflux and enhances esophageal function.
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