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Cerebral ventricular size in panic disorder.

T W Uhde, C H Kellner

Journal of Affective Disorders

|March 1, 1987

Summary

This summary is machine-generated.

This study found that patients with panic disorder had normal brain structures. However, longer benzodiazepine use was linked to changes in the ventricular-brain ratio.

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Area of Science:

Neuroimaging
Psychiatry

Background:

Panic disorder is a common psychiatric condition.
Brain imaging studies in panic disorder have yielded mixed results.

Purpose of the Study:

To investigate brain structure in patients with panic disorder using computed axial brain tomography.
To examine the relationship between brain imaging findings and benzodiazepine use duration.

Main Methods:

Computed axial brain tomography (CT scan) was performed on 25 patients diagnosed with panic disorder.
Ventricular-brain ratio (VBR) was calculated and compared to established norms.

Main Results:

Patients with panic disorder exhibited a normal ventricular-brain ratio (VBR) when compared to published data.

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A statistically significant correlation was identified between the duration of benzodiazepine use and the VBR.

Conclusions:

Brain structure, as assessed by VBR, appears to be largely unaffected in patients with panic disorder.
The duration of benzodiazepine treatment may influence brain structure, specifically the VBR, in individuals with panic disorder.