A Review of Meningococcal Disease and Vaccination Recommendations for Travelers

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Lidia C Serra1, Laura J York2, Amgad Gamil3

  • 1Pfizer Vaccines, Medical Development, Scientific and Clinical Affairs, Collegeville, PA, USA. Lidia.Olveira@pfizer.com.

Infectious Diseases and Therapy
|March 19, 2018
PubMed

Insights

International travel increases risk for invasive meningococcal disease (IMD). Quadrivalent vaccines, like MenACWY-TT, are crucial for preventing IMD in travelers, especially to high-risk regions.

Area of Science:

  • Travel medicine
  • Infectious disease epidemiology
  • Vaccinology

Background:

  • International travel has increased, exposing more individuals to regions with endemic or outbreak-prone meningococcal disease.
  • Invasive meningococcal disease (IMD) poses risks including rapid progression, poor outcomes, and potential outbreaks, with up to 22% fatality.
  • The funding for this review was provided by Pfizer Inc.

Purpose of the Study:

  • To review the epidemiology of IMD in international travelers.
  • To identify geographic regions of concern for travelers regarding IMD.
  • To summarize available meningococcal vaccines and country-specific recommendations for travelers.

Main Methods:

  • Literature review focusing on IMD epidemiology in travelers.
  • Analysis of geographic risk factors for IMD.
  • Summary of current meningococcal vaccine recommendations by country and age group.

Main Results:

  • IMD remains a concern for travelers despite vaccine availability.
  • Specific geographic regions present higher risks for travelers.
  • Quadrivalent meningococcal vaccines, particularly MenACWY-TT, are emphasized for traveler protection.

Conclusions:

  • Vaccination is the primary strategy for preventing IMD in international travelers.
  • Travelers should be aware of IMD risks and consult country-specific vaccination guidelines.
  • MenACWY-TT vaccine offers important protection against IMD for those traveling to high-risk areas.
Keywords:
AdultsInvasive meningococcal diseaseMeningococcal vaccinesTravelers

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