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Published on: September 19, 2019
[A skin ulcer infection due to Rhodotorula mucilaginosa in an immunocompromised child]
H Tligui1, W Oudaina1, S El Ftouh1
1Research Laboratory of Ibn Sina Hospital, CHU Ibn Sina, hôpital d'enfants Rabat, Rabat Institut, BP 6527, rue Lamfadel-Cherkaoui, Rabat, Maroc.
Abstract:
Human cutaneous infections due to Rhodotorula species as an emerged pathogens yeasts are rarely reported, particularly in skin folds, with the ability to infect immunocompromised as well as immunocompetent patient. In present case, we describe a fungal cutaneous infection due to Rhodotorula mucilaginosa in immunocompromised child, the patient has been diagnosed with retinoblastoma; the diagnosis was established by the cytological and clinical examination. However, the cytological examination found fungal forms. The diagnosis relies on the microbiological analysis of clinical samples but the interpretation of a positive culture should be part of and over all analysis that integrate clinical symptoms and risk factors. Most of cases of infection due to Rhodotorula were associated with central venous catheter in patients who were receiving immunosuppressors and cyotoxic drugs. The antifungal susceptibility testing was done; a fluconazol and ketoconazol showed susceptibles. The patient was treated by combinate antifungal therapy and empirical antimicrobial regimen for prophylaxis.
Insights
Rhodotorula mucilaginosa, an emerging fungal pathogen, caused a rare skin infection in an immunocompromised child with retinoblastoma. Prompt diagnosis and combination antifungal therapy were crucial for successful treatment.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Dermatology
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