Oral, systemic and socioeconomic factors associated with preterm birth

Anna Clara F Vieira1, Cláudia M C Alves1, Vandilson P Rodrigues1

  • 1Postgraduate Program in Dentistry, Dental School, Federal University of Maranhão, São Luis, MA, Brazil.

Insights

Preterm birth rates are rising globally. This study found no link between dental caries and preterm birth, but identified maternal education and hypertension as significant risk factors for premature delivery.

Area of Science:

  • Obstetrics and Gynecology
  • Public Health
  • Dental Public Health

Background:

  • Global increase in preterm birth rates necessitates identification of associated risk factors.
  • Preterm birth complications significantly impact healthcare costs and national health systems.
  • Understanding preterm birth determinants is crucial for developing effective prevention strategies.

Purpose of the Study:

  • To investigate oral, systemic, and socioeconomic factors linked to preterm birth in postpartum women.
  • To analyze the association between dental caries and preterm birth.
  • To identify key predictors of prematurity in a cohort of 279 women.

Main Methods:

  • Case-control study design comparing women with preterm birth (cases) and term birth (controls).
  • Data collection via questionnaires, medical records, and intra-oral clinical examinations.
  • Dental caries assessed using World Health Organization criteria; oral biofilm evaluated by visible plaque index.

Main Results:

  • No statistically significant association was found between dental caries and preterm birth (OR=1.08, p=0.90).
  • Maternal educational level (OR=2.56, p=0.01) and arterial hypertension (OR=2.32, p=0.01) were significantly associated with preterm birth.
  • Dental caries prevalence was high (62.3% in cases, 62.5% in controls).

Conclusions:

  • Dental caries, while common, is not a significant predictor of preterm birth in this population.
  • Lower maternal education and presence of arterial hypertension are key risk factors for preterm birth.
  • Further research into socioeconomic and systemic factors influencing preterm birth is warranted.
Abstract

Related Concept Videos

Oral Drug Delivery Systems: Continuous-Release Systems01:26

Oral Drug Delivery Systems: Continuous-Release Systems

Continuous-release drug delivery systems offer a strategic approach to maintaining therapeutic drug levels over extended periods following oral administration. By modulating the release rate of active pharmaceutical ingredients, these systems minimize fluctuations in plasma concentrations, which enhances clinical efficacy and reduces the need for frequent dosing. Such characteristics make them particularly advantageous in managing chronic diseases where patient adherence and stable drug...
1
Oral Drug Delivery Systems: Delayed-Release Systems01:11

Oral Drug Delivery Systems: Delayed-Release Systems

Delayed-release drug delivery systems are specialized pharmaceutical formulations designed to postpone the release of active compounds until the drug reaches a specific region of the gastrointestinal (GI) tract, typically the intestine. These systems are essential for drugs that may cause gastric irritation, are unstable in acidic environments, or need to exert therapeutic effects locally in the intestinal or colonic regions.The core feature of delayed-release systems is the use of enteric...
2
Oral Drug Delivery Systems: Introduction01:23

Oral Drug Delivery Systems: Introduction

Oral drug delivery is the most common route of administration due to its convenience, cost-effectiveness, and high patient compliance. It enables precise formulation to ensure proper drug dosage and bioavailability. The development of oral dosage forms considers drug properties such as solubility, stability, and absorption to optimize therapeutic efficacy.Tablets, capsules, liquids, and chewable formulations enhance drug stability, mask undesirable tastes, and improve patient experience.
1
Birth Control Methods01:22

Birth Control Methods

Vasectomy is a surgical form of male sterilization that involves severing and sealing the vasa deferentia, preventing sperm from mixing with semen during ejaculation. Because a vasectomy does not impact the testes' ability to produce testosterone, hormone levels, libido, and sexual function generally remain unchanged. While vasectomy is highly effective in preventing pregnancy, with a success rate near 99.85%, rare cases of recanalization (spontaneous reconnection) can occur. Although...
6.9K
Modified-Release Drug Delivery Systems: Influencing Factors01:20

Modified-Release Drug Delivery Systems: Influencing Factors

Modified-release drug delivery systems are designed to optimize the therapeutic effect of drugs by minimizing side effects, reducing the dosage required, and controlling drug release to align with pharmacokinetic and pharmacodynamic needs. The system depends on two key factors: the drug's release from the formulation and its movement through the body to the target site. Unlike conventional dosage forms, where absorption is the limiting step, the rate of drug release is the key determinant in...
3
Oral Cavity01:11

Oral Cavity

The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
3.2K