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Updated: Feb 13, 2026

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
Published on: January 31, 2025
Gallbladder Nonvisualization in Cholecystectomy: A Factor for Conversion
Daniel R Slack1, Shaunda Grisby2, Uzoamaka Kimberly Dike2
1Surgery Department, Waterbury Hospital, Waterbury, Connecticut.
Nonvisualization of the gallbladder during minimally invasive cholecystectomy significantly increases complication and conversion risks. Early recognition of nonvisualization can prompt surgeons to convert to open procedures, enhancing patient safety.
Area of Science:
- Surgical Innovation
- Minimally Invasive Surgery
- Patient Safety
Background:
- Minimally invasive cholecystectomies have known risk factors for complications and conversion.
- Nonvisualization of the gallbladder (GB) during surgery has not been previously identified as a specific risk factor.
Purpose of the Study:
- To investigate if intraoperative nonvisualization of the GB is associated with increased complications and conversion rates.
- To determine if nonvisualization can serve as an early indicator for higher-risk procedures.
Main Methods:
- Retrospective review of minimally invasive cholecystectomies from January 2015 to April 2016.
- Surgeons completed post-operative surveys detailing intraoperative findings.
- Analysis of outcomes including conversion rates, intraoperative complications, and estimated blood loss (EBL).
Main Results:
- Conversion rate was 37% in cases with nonvisualized GBs versus 0% in visualized GBs (P = .001).
- Significantly higher rates of GB perforations (74% vs 13%), omental vessel bleeding (16% vs 0%), and EBL (46 mL vs 29 mL) were observed with nonvisualization (P = .001).
Conclusions:
- Intraoperative nonvisualization of the GB is a significant risk factor for complications and conversion in minimally invasive cholecystectomy.
- Recognizing nonvisualization can aid surgeons in early conversion to open surgery, improving patient safety.
- Further randomized controlled trials are recommended to validate these findings.
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