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Updated: Feb 13, 2026

Electroporation of Craniofacial Mesenchyme
Published on: November 28, 2011
Craniofacial Actinomyces osteomyelitis evolving from sinusitis
Joseph Y Shen1, Neal D Futran2, Maya G Sardesai2
1Department of Dermatology, Stanford University, Stanford, CA, USA.
Abstract:
Craniofacial Actinomyces osteomyelitis progression is rare, as patients are soon treated. A 56-year-old male smoker presented with sinusitis and was managed medically. This patient failed to follow up and presented 1 year later with erosive bony disease. He was managed medically and surgically; however, his disease evolved to include his midface, skull base, and cranium. He underwent staged debridement and free tissue reconstruction. His disease is controlled but not cured. The literature includes case reports and small series describing limited disease treated successfully with surgical and medical management. Although craniofacial Actinomyces osteomyelitis is uncommon, it can become debilitating. This case demonstrates how craniofacial Actinomyces osteomyelitis can progress and highlights the benefit of a multidisciplinary approach.
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