Related Experiment Video
Updated: Feb 13, 2026

Zebrafish Model of Neuroblastoma Metastasis
Published on: March 14, 2021
Pediatric mandibular metastasis: A rare finding of neuroblastoma
Gregory Wade1, Jonathan Revels2, Lauren Hartman3
1Department of Radiology, Eastern Virginia Medical School, Norfolk, VA, USA.
Abstract:
We present a case of metastatic neuroblastoma to the mandible in an 11-month-old patient presenting with worsening right-sided proptosis and scalp swelling after a fall 2 weeks prior. Initial evaluation with computed tomography of the head demonstrated soft tissue masses centered at the right sphenoid and right mandible. These masses proved to be metastatic lesions from an intra-abdominal neuroblastoma. Review of the literature revealed 20 cases of neuroblastoma metastasis to the mandible over the past 70 years. To our knowledge, our patient is the youngest reported case with asymptomatic mandibular metastasis related to neuroblastoma and the first to be characterized with magnetic resonance imaging.
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