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Updated: Feb 13, 2026

Method for Obtaining Primary Ovarian Cancer Cells From Solid Specimens
Published on: February 4, 2014
Primary small cell ovarian cancer of pulmonary type: A case report
Emmanouil Kalampokas1, Vijay Sharma2, Tanja Gagliardi3
1Department of Gynecologic Oncology, Ward 315, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, United Kingdom.
Background:
Primary small cell ovarian cancer of pulmonary type (SCCOPT) is a rare aggressive ovarian tumour with an incidence of <1%, usually occurring in perimenopausal or postmenopausal women and known to have a poor prognosis. Current treatment is platinum based but has not resulted in long term survival.
Case Presentation:
We report a case of a 77-year old Caucasian woman who presented initially with a one-week history of abdominal discomfort with raised inflammatory markers and Ca125 of 50 μ/ml. Calcium levels were normal. She underwent primary debulking surgery, and histology showed a tumour comprising areas of classical small-cell carcinoma morphology. 6 cycles of adjuvant chemotherapy with carboplatin was offered. Relapsed/progressive disease was noted after 3 months of chemotherapy and patient died 7 months after treatment completion.
Conclusions:
SCCOPT is a rare aggressive malignancy with majority of the women having an overall survival of 2 years. There is no clear consensus for the diagnosis and optimal treatment.
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