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Fatigue following Paediatric Acquired Brain Injury and its Impact on Functional Outcomes: A Systematic Review
Jake Wilkinson1,2, Nohely Lee Marmol1,3, Celia Godfrey1
1Murdoch Children's Research Institute, Flemington Road, Parkville, VIC, 3052, Australia.
Neuropsychology Review
|March 20, 2018
Summary
Childhood acquired brain injury (ABI) frequently causes fatigue, impacting academics and social-emotional well-being. More research is needed to understand fatigue trajectories and effective management strategies for pediatric patients.
Area of Science:
- Neuroscience
- Pediatrics
- Rehabilitation Medicine
Background:
- Fatigue is a common, yet under-researched, sequela of childhood acquired brain injury (ABI).
- The occurrence, duration, and functional impact of fatigue in pediatric ABI populations remain uncertain.
- Existing research lacks a comprehensive summary focusing specifically on fatigue in this demographic.
Purpose of the Study:
- To systematically review and synthesize existing research on fatigue following pediatric acquired brain injury (ABI).
- To consolidate findings on the prevalence, characteristics, and impact of fatigue in children with ABI.
- To identify potential areas for future research and management strategies.
Main Methods:
- A systematic literature search was conducted across PsycInfo, Medline, and CINAHL databases.
- Inclusion and exclusion criteria were applied to identify relevant studies focusing on pediatric ABI and fatigue.
- Nine papers met the criteria, categorized by injury type: traumatic brain injury (TBI), meningitis, brain tumors, and mixed ABI.
Main Results:
- Fatigue is a significant issue for a substantial proportion of children with ABI, irrespective of the injury cause.
- Fatigue was associated with negative outcomes, including poor academic performance, reduced physical activity, and social-emotional difficulties.
- More severe injuries correlated with higher fatigue levels and poorer overall outcomes.
Conclusions:
- Fatigue is a prevalent and impactful problem in children with acquired brain injuries.
- Severity of injury is linked to increased fatigue and worse functional outcomes.
- Further research is essential to understand fatigue trajectories and establish evidence-based management guidelines for pediatric ABI survivors.
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