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The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
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Related Experiment Video

Updated: Feb 13, 2026

Impression Cytology of the Lid Wiper Area
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Nasal cytology.

M Gelardi1, C Cavaliere2, L Jannuzzi1

  • 1Section of Otolaryngology, University Department of Basic Medical Science, Neuroscience and Sensory Organs, Bari, Italy.

Journal of Biological Regulators and Homeostatic Agents
|March 20, 2018
PubMed
Summary
This summary is machine-generated.

Nasal cytology is a simple, affordable diagnostic method for rhinitis. This painless technique analyzes nasal cells to identify inflammation and differentiate conditions across all ages.

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Area of Science:

  • Allergy and Immunology
  • Otorhinolaryngology
  • Cytopathology

Background:

  • Rhinitis diagnosis benefits from detailed phenotypic characterization.
  • Nasal cytology offers a method to assess nasal mucosa cell populations.

Purpose of the Study:

  • To evaluate nasal cytology as a diagnostic tool for rhinitis.
  • To detail the methodology and applications of nasal cytology.

Main Methods:

  • Painless cell sampling from the inferior turbinate using a curette.
  • Staining with May-Grünwald-Giemsa (MGG) and microscopic examination (1000x oil).
  • Detection and quantification of inflammatory cells (eosinophils, mast cells, neutrophils, lymphocytes).

Main Results:

  • Nasal cytology effectively detects inflammatory cells in allergic and non-allergic rhinitis.
  • The technique is non-invasive, inexpensive, and repeatable.

Conclusions:

  • Nasal cytology is an accessible diagnostic method for various age groups.
  • It aids in differentiating rhinitis pathologies and evaluating treatment responses.