Related Experiment Video
Updated: Feb 13, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
Published on: November 5, 2016
The Impact of Opening a Medical Step-Down Unit on Medically Critically Ill Patient Outcomes and Throughput: A
Hayley B Gershengorn1,2, Carri W Chan3, Yunchao Xu4
1Division of Pulmonary, Allergy, Critical Care, and Sleep Medicine, University of Miami Miller School of Medicine, University of Miami and Jackson Memorial Hospitals, Miami, FL, USA.
Objective:
To understand the impact of adding a medical step-down unit (SDU) on patient outcomes and throughput in a medical intensive care unit (ICU).
Design:
Retrospective cohort study.
Setting:
Two academic tertiary care hospitals within the same health-care system.
Patients:
Adults admitted to the medical ICU at either the control or intervention hospital from October 2013 to March 2014 (preintervention) and October 2014 to March 2015 (postintervention).
Interventions:
Opening a 4-bed medical SDU at the intervention hospital on April 1, 2014.
Measurements And Main Results:
Using standard summary statistics, we compared patients across hospitals. Using a difference-in-differences approach, we quantified the association of opening an SDU and outcomes (hospital mortality, hospital and ICU length of stay [LOS], and time to transfer to the ICU) after adjustment for secular trends in patient case-mix and patient-level covariates which might impact outcome. We analyzed 500 (245 pre- and 255 postintervention) patients in the intervention hospital and 678 (323 pre- and 355 postintervention) in the control hospital. Patients at the control hospital were younger (60.5-60.6 vs 64.0-65.4 years, P < .001) with a higher severity of acute illness at the time of evaluation for ICU admission (Sequential Organ Failure Assessment score: 4.9-4.0 vs 3.9-3.9, P < .001). Using the difference-in-differences methodology, we identified no association of hospital mortality (odds ratio [95% confidence interval]: 0.81 [0.42 to 1.55], P = .52) or hospital LOS (% change [95% confidence interval]: -8.7% [-28.6% to 11.2%], P = .39) with admission to the intervention hospital after SDU opening. The ICU LOS overall was not associated with admission to the intervention hospital in the postintervention period (-23.7% [-47.9% to 0.5%], P = .06); ICU LOS among survivors was significantly reduced (-27.5% [-50.5% to -4.6%], P = .019). Time to transfer to ICU was also significantly reduced (-26.7% [-44.7% to -8.8%], P = .004).
Conclusions:
Opening our medical SDU improved medical ICU throughput but did not affect more patient-centered outcomes of hospital mortality and LOS.
More Related Videos
Related Concept Videos
Inhaled Medications
Electric Potential and Potential Difference
When a test charge moves from the initial to the final position, the electric potential difference between those positions is defined as the ratio of the change in the potential energy to the charge on the...
Difference from Background: Limit of Detection
The LOD indicates the presence or absence...
Identifying Statistically Significant Differences: The F-Test
Sum and Difference OpAmps
A summing amplifier, or an adder, utilizes an op-amp to merge multiple input signals into a single output signal. When audio signals are introduced into its input channels, the input resistors initiate currents that traverse feedback resistors, resulting in an output voltage. Applying Kirchhoff's current...
Difference Equation Solution using z-Transform
The z-transform facilitates handling delayed signals by shifting the signal in the z-domain, which corresponds to delaying the signal in the time domain, and advancing signals by similarly shifting in the...

