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Related Experiment Video

Updated: Feb 13, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

Published on: December 10, 2016

Clostridium difficile Exposures, Colonization, and the Microbiome: Implications for Prevention.

Sara L Revolinski¹, L Silvia Munoz-Price²

¹1Department of Pharmacy,Froedtert Hospital,Milwaukee,Wisconsin.

Infection Control and Hospital Epidemiology

|March 20, 2018

Summary

New research explores Clostridium difficile epidemiology, including asymptomatic colonization and community infections. It also examines environmental and animal spread, gut microbiome interactions, and future prevention strategies using advanced sequencing techniques.

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Last Updated: Feb 13, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291

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Published on: December 10, 2016

A Protocol to Characterize the Morphological Changes of Clostridium difficile in Response to Antibiotic Treatment

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Published on: May 25, 2017

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Culturing and Maintaining Clostridium difficile in an Anaerobic Environment

Published on: September 14, 2013

Area of Science:

Infectious Diseases
Epidemiology
Microbiology

Background:

Clostridium difficile infections (CDI) remain a significant public health concern.
Understanding the epidemiology of CDI is crucial for effective prevention and control.
Recent advancements necessitate an updated review of CDI epidemiology.

Purpose of the Study:

To summarize recent epidemiological findings on Clostridium difficile.
To explore the role of asymptomatic colonization and community-associated infections.
To discuss the impact of novel techniques on CDI prevention.

Main Methods:

Literature review of recent studies on Clostridium difficile epidemiology.
Synthesis of findings related to colonization, infection, and environmental factors.
Analysis of the potential of high-throughput sequencing for CDI prevention.

Main Results:

New data on asymptomatic Clostridium difficile colonization and community-associated infections are available.
Environmental contamination and animal colonization patterns are increasingly understood.
Interactions between Clostridium difficile and the gut microbiome are a key area of research.

Conclusions:

Continued research into Clostridium difficile epidemiology is vital.
High-throughput sequencing and other advanced techniques show promise for preventing CDI.
A comprehensive understanding of transmission routes is essential for public health strategies.