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[Various immunologic indices of children and adolescents with type I diabetes mellitus]
An experimental study was performed in patients with Type I diabetes mellitus of various duration in order to determine the levels of total T-lymphocytes (TTC) and T-lymphocytes forming an active rosette (TLAR) and to find possible correlation between the level of the above cells and titers of anticytoplasmatic antibodies (ACA) versus islet cells. The TLAR level in patients with disease of less than 2 mos. duration was significantly lowered (P less than 0.001) as compared to the control one. In ACA determination there was a decrease in positive cases with a growing period of disease (P less than 0.01). Correlation between the TLAR level and ACA titers was absent.
An experimental study was performed in patients with Type I diabetes mellitus of various duration in order to determine the levels of total T-lymphocytes (TTC) and T-lymphocytes forming an active rosette (TLAR) and to find possible correlation between the level of the above cells and titers of anticytoplasmatic antibodies (ACA) versus islet cells. The TLAR level in patients with disease of less than 2 mos. duration was significantly lowered (P less than 0.001) as compared to the control one. In ACA determination there was a decrease in positive cases with a growing period of disease (P less than 0.01). Correlation between the TLAR level and ACA titers was absent.