Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genomics02:02

Genomics

40.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
40.9K
Key Techniques in Microbiology01:19

Key Techniques in Microbiology

2.5K
Aseptic techniques prevent contamination, ensure experimental accuracy, and protect researchers and microbial cultures. These techniques are essential in clinical, industrial, and research settings where sterility is required.Maintaining Sterility in Laboratory PracticesScientists maintain sterility by sterilizing tools with heat or chemicals, disinfecting work surfaces, and handling cultures in controlled environments. Working near an open flame or within a laminar flow hood reduces the risk...
2.5K
Key Elements for Plant Nutrition02:35

Key Elements for Plant Nutrition

24.4K
Like all living organisms, plants require organic and inorganic nutrients to survive, reproduce, grow and maintain homeostasis. To identify nutrients that are essential for plant functioning, researchers have leveraged a technique called hydroponics. In hydroponic culture systems, plants are grown—without soil—in water-based solutions containing nutrients. At least 17 nutrients have been identified as essential elements required by plants. Plants acquire these elements from the...
24.4K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

37.3K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
37.3K
Genome Size and the Evolution of New Genes03:21

Genome Size and the Evolution of New Genes

9.2K
While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
9.2K
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

277
In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
277

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Australian parents' perspectives on extended genomic screening: what information to return and when?

European journal of human genetics : EJHG·2026
Same author

Personal values, professional responsibilities and non-invasive prenatal testing: reflections of genetic counsellors in Australia.

Journal of community genetics·2026
Same author

Harmonization of Health Data Governance, Oversight, and Policy: Reimagining Stewardship.

Healthcare management forum·2026
Same author

Contribution of Risk Factors, Including Polygenic Score, to the Multifactorial Risk Assessment for the Implementation of Personalized Breast Cancer Screening: Insights from the PERSPECTIVE: Integration and Implementation Project.

Cancers·2026
Same author

Genomic newborn screening: a scoping review of the field's evolution and associated ethical, legal, and social implications.

European journal of human genetics : EJHG·2026
Same author

Genomic newborn screening: data retention for research and clinical reuse.

European journal of human genetics : EJHG·2026

Related Experiment Video

Updated: Feb 13, 2026

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
12:39

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types

Published on: December 10, 2012

11.7K

Key Implications of Data Sharing in Pediatric Genomics.

Vasiliki Rahimzadeh1, Christoph Schickhardt2, Bartha M Knoppers1

  • 1Centre of Genomics and Policy, McGill University, Montreal, Quebec, Canada.

JAMA Pediatrics
|March 20, 2018
PubMed
Summary

Sharing children's genomic data is crucial for accurate interpretation. The Key Implications for Data Sharing (KIDS) framework addresses ethical and legal challenges to facilitate this vital data sharing.

More Related Videos

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
08:31

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'

Published on: May 26, 2013

11.5K
Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.6K

Related Experiment Videos

Last Updated: Feb 13, 2026

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
12:39

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types

Published on: December 10, 2012

11.7K
Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
08:31

Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'

Published on: May 26, 2013

11.5K
Guidelines for Elective Pediatric Fiberoptic Intubation
11:19

Guidelines for Elective Pediatric Fiberoptic Intubation

Published on: January 17, 2011

18.6K

Area of Science:

  • Genomics
  • Bioethics
  • Pediatric Health

Background:

  • Accurate interpretation of pediatric whole-genome and whole-exome sequences requires robust comparison with variant reference databases.
  • The effectiveness of these comparisons depends on the routine sharing of pediatric genomic and associated clinical data.
  • Current ethical-legal policies inadequately address the routine sharing of children's genomic data.

Purpose of the Study:

  • To detail the ethical, legal, and social implications of sharing genomic and clinical data involving children.
  • To develop a framework addressing the complexities of pediatric genomic data sharing.
  • To provide actionable points for consideration in establishing routine data sharing practices.

Main Methods:

  • Convened an interdisciplinary Paediatric Task Team within the Global Alliance for Genomics and Health.
  • Presented initial points for consideration at a Paediatric Task Team meeting.
  • Developed the Key Implications for Data Sharing (KIDS) framework based on group feedback and literature appraisal.

Main Results:

  • Identified key ethical and legal considerations for sharing children's genomic data.
  • Developed the KIDS framework, a structured set of points to consider for pediatric genomics data sharing.
  • Categorized the framework into four primary themes: children's involvement, parental consent, benefit-risk balance, and data protection/release.

Conclusions:

  • Routine sharing of pediatric genomic and clinical data is essential for accurate interpretation.
  • The KIDS framework provides a comprehensive approach to navigate the ethical and legal landscape of pediatric data sharing.
  • Addressing children's involvement, consent, risks, benefits, and data protection is critical for advancing pediatric genomics research and clinical practice.