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Updated: Feb 13, 2026

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A Method to Assess Bacteriocin Effects on the Gut Microbiota of Mice
Published on: July 25, 2017
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Not so Splendid for the Gut Microbiota
Benoit Chassaing1,2, Andrew T Gewirtz1
1Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences.
Inflammatory Bowel Diseases
|March 20, 2018
Abstract:
A critically important new study by leading inflammatory bowel disease (IBD) researcher Fabio Cominelli and colleagues reveals that, in mice, the artificial sweetener SPLENDA deleteriously impacts the intestinal microbiota in a manner that promotes Crohn's-type disease in genetically susceptible hosts. These results suggest that consumption of this product may be a risk factor for IBD.
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