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Updated: Feb 13, 2026

Primary Tumor and MEF Cell Isolation to Study Lung Metastasis
Published on: May 20, 2015
[Multiple lung carcinoma: Primary or intrapulmonary metastasis?]
Lucie Ravella1, Marc Barritault1, Pierre-Paul Bringuier1
1Service de pathologie, multi-sites des hospices civils de Lyon, Site Est, CHU de Lyon, 59, boulevard Pinel, 69677 Bron, France; Université Lyon 1, 69100 Villeurbanne, France.
Abstract:
Multiple lung carcinomas are 5 to 11,5% of lung carcinomas. The distinction between primary lung carcinomas from carcinomas with intrapulmonary metastasis is essential for optimal patient management. The histopathological analysis is very useful but it has to be completed by genotypic assessment using molecular biology (NGS). Molecular biology can also identify genetic alterations with therapeutic implications. We present the case of a patient with a history of surgery for multiple lung carcinomas diagnosed from 2013 to 2017.
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