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Updated: Feb 13, 2026

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
Published on: September 26, 2016
Iliac crest bone grafting for mandibular reconstruction: 10-year experience outcomes
Timothy M Osborn1,2, Deeb Helal2, Pushkar Mehra1,2
1Dept. of Oral & Maxillofacial Surgery, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.
Nonvascularized iliac crest bone grafts (NVBG) show high success in mandibular reconstruction, especially for defects under 9 cm. Larger defects are less predictable but manageable with adjuncts, with graft size being a key factor in outcomes.
Area of Science:
- Oral and Maxillofacial Surgery
- Reconstructive Surgery
- Bone Grafting
Background:
- Mandibular defects require complex reconstruction.
- Nonvascularized iliac crest bone grafts (NVBG) are a common option.
- Evaluating long-term outcomes is crucial for optimizing surgical techniques.
Purpose of the Study:
- To assess the 10-year efficacy of NVBG for mandibular reconstruction.
- To identify factors influencing reconstruction success and complications.
- To provide evidence-based recommendations for NVBG use in mandibular defects.
Main Methods:
- Retrospective analysis of 60 patients undergoing mandibular reconstruction with NVBG.
- Classification of defects into continuity (CD) and non-continuity (NCD).
- Analysis of various factors including defect size, pathology, and surgical approach; success defined by graft maintenance and absence of infection.
Main Results:
- High success rates: 87% for CD and 82.1% for NCD.
- Defect size significantly impacted success; defects >9 cm were associated with failure.
- Complications were predominantly minor (43 cases) versus major (4 cases).
Conclusions:
- NVBG is highly successful for non-cancerous mandibular continuity defects <9 cm.
- For defects >9 cm, NVBG is less predictable but can be considered with adjunctive materials.
- Symphysis involvement did not significantly affect success rates when following established protocols.
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