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Updated: Feb 13, 2026

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
Published on: September 26, 2016
Iliac crest bone grafting for mandibular reconstruction: 10-year experience outcomes
Timothy M Osborn1,2, Deeb Helal2, Pushkar Mehra1,2
1Dept. of Oral & Maxillofacial Surgery, Boston University Henry M. Goldman School of Dental Medicine, Boston, MA, USA.
Purpose:
To evaluate 10-year patient data related to mandibular reconstruction with NVBG at a tertiary academic center.
Patients And Methods:
Sixty patients with mandibular mandibular reconstruction were included. Patients were divided to continuity defect and non-continuity defect. Pathology lesion, immediate reconstruction, smoking habit, medical comorbidities, site and size of the defect, surgical approach, intraoperative perforation, cadaveric bone use, and maxilla-mandibular fixation use were analyzed as factors of influence on success. Success was defined as maintenance of more than 50% of graft for non-continuity defects (NCD) and bone continuity and stability for continuity defect (CD), and absence of infection on last follow up upon clinical and radiographic examination. Complications were classified as minor or major.
Results:
The reconstruction was successful in 28 (87%) of CD patients and 23 (82.1%) of NCD patients. Analyses showed that the size of defect was significantly associated with failure. All 4 failed cases of CD had defects more than 9 cm. Four patients had major complications and 43 minor complication.
Conclusions:
Nonvascularized iliac crest bone grafts are highly successful in mandibular continuity reconstruction for non-Cancer patients and should be considered as first choice for defects less than 9 cm. They are less predictable for defects larger than 9 cm but can be considered in these cases with osteoconductive cribs. Symphysis involvement may or may not be associated with lower success rate if our protocol is followed.
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