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A mini review: garlic extract and vascular diseases

Yuequan Zhu1, Raja Anand2, Xiaokun Geng1,2,3

  • 1a China-America Institute of Neuroscience, Beijing Luhe Hospital , Capital Medical University , Beijing , China.

Neurological Research
|March 21, 2018
PubMed

Insights

Garlic may help manage vascular diseases by favorably affecting atherosclerosis, hypertension, and diabetes. Research explores its potential to reduce risks of heart attack and stroke.

Area of Science:

  • Cardiovascular Science
  • Nutritional Science
  • Pharmacology

Background:

  • Vascular diseases, characterized by narrowed blood vessels, increase risks of myocardial infarction and ischemic stroke.
  • Atherosclerosis, hypertension, and diabetes are key risk factors contributing to cardiovascular and cerebral complications.
  • Garlic has a long history as a natural remedy, with emerging research on its therapeutic effects.

Purpose of the Study:

  • To review the current literature on garlic's effects in patients with vascular disease.
  • To elucidate the mechanisms underlying garlic's anti-hypertensive, anti-hyperlipidemic, and hypoglycemic effects.
  • To highlight garlic's potential as an adjuvant therapy for common health conditions.

Main Methods:

  • Literature review of existing research on garlic and vascular disease.
  • Analysis of studies investigating garlic's impact on atherosclerosis, hypertension, and diabetes.
  • Focus on the pathophysiological mechanisms of garlic's beneficial effects.

Main Results:

  • Garlic demonstrates favorable effects on atherosclerosis, hypertension, and diabetes.
  • Evidence suggests garlic can decrease the risk of myocardial infarction and ischemic stroke.
  • Mechanisms of action for garlic's anti-hypertensive, anti-hyperlipidemic, and hypoglycemic properties are being identified.

Conclusions:

  • Garlic shows promise in managing vascular diseases and associated risk factors.
  • Further research is warranted to explore garlic's role as an adjuvant to conventional pharmacotherapy.
  • Understanding garlic's mechanisms can aid in developing integrated treatment strategies for vascular conditions.

Keywords:
Atherosclerosisdiabeteshypertensionhypolipidemic and hypocholesterolemic effectinflammationoxidative

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