Related Experiment Video
Updated: Feb 13, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Natural history of a squamous cell carcinoma of the lower lip
Abstract:
Natural history of a squamous cell carcinoma of the lower lip.
Objective:
In lip cancer cases without significant co-morbidities, curative treatment is preferable to palliative; although, the patient may refuse care. This case report describes the natural progression of squamous cell carcinoma (SCC) of the lower lip.
Case Report:
A 76-year-old, non-smoker, male farmer had a lesion on his left lower lip that was clinically and histological proven to be a T₁N₀Mx SCC. During the first consultation, no cervical lymph nodes were palpated. Initially, the patient himself treated the SCC with udder ointment. Three years later, he had difficulties eating solid food and his meals consisted mainly of liquid nutrients. The lesion initially progressed slowly, but grew fast after 3 years and Even in this mutilating stage, the patient refused treatment.
Conclusion:
Despite the tumor stage and co-morbidities, the patient makes the treatment decisions; therefore, the implications of these decisions must be discussed.
Related Concept Videos
What is Evolutionary History?
Life Histories
History of Microbiology
What is Natural Selection?
Nature and Nurture
Nursing Assessment of the Genitourinary System I: Health History

