Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Predicting Molecular Geometry

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries

Major Hormones and Their Functions

Major Hormones and Their Functions

Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...

Major Losses in Pipes

Major Losses in Pipes

When a fluid flows through a pipe, it experiences energy losses due to frictional resistance along the pipe walls, known as major losses. These energy losses result in a pressure drop, which varies based on the flow conditions — whether laminar or turbulent — and the specific physical properties of the fluid and pipe.
Fluid flow can be classified as laminar or turbulent, primarily based on the Reynolds number. This dimensionless number reflects the relative influence of inertial to viscous...

Major Organs of the Digestive System

Major Organs of the Digestive System

The digestive system is responsible for the ingestion of food, secretion of enzymes, mixing and digesting food, absorption of the nutrients and defecation. The human digestive system consists of two major parts: the gastrointestinal tract and the accessory digestive organs.
Gastrointestinal tract:

Muscles of the Pelvic Floor and Perineum

Muscles of the Pelvic Floor and Perineum

The muscles of the pelvic floor and perineum are crucial for supporting the pelvic organs, controlling continence, and aiding in sexual function, childbirth, and core stability. They are typically divided into the superficial perineal layer and the deep pelvic floor layer.
Perineal Layer
The perineum is a diamond-shaped area below the pelvic diaphragm, divided into an anterior urogenital triangle that contains the external genitals and a posterior anal triangle housing the anus. The urogenital...

Prediction Intervals

Prediction Intervals

The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Small Femoral Nails and the Development of a Nonunion: A Case-Control Study.

Orthopedics·2026

Same author

Salvage Posterior C1-C2 Fusion for Odontoid Nonunion After Failed Nonoperative Management: A Propensity Score-Matched Comparison with Primary Fusion.

Journal of clinical medicine·2026

Same author

Signal Over Noise: A Novel Use of Subtraction CT for Pelvic Active Bleeding.

Radiology·2026

Same author

Randomised controlled trial comparing antibiotic cement bead pouch versus negative pressure wound therapy for the management of severe open tibia fracture wounds: Beads versus VAC (BvV) protocol.

BMJ open·2026

Same author

Outcomes of Triple-Tapered Collared Cementless versus Cemented Stems in Total Hip Arthroplasty for Femoral Neck Fracture: A Propensity Score Overlap-Weighted Cohort Study.

The Journal of arthroplasty·2026

Same author

Adverse Mental Health Outcomes after Modern External Ring Fixation Versus Internal Fixation for Severe Open Tibia Fractures: A Secondary Analysis of the FIXIT Study.

Journal of orthopaedic trauma·2026

Search research articles

Related Experiment Video

Updated: Feb 13, 2026

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

Published on: May 31, 2021

CT Prediction Model for Major Arterial Injury after Blunt Pelvic Ring Disruption.

David Dreizin¹, Uttam Bodanapally¹, Alexis Boscak¹

¹From the Department of Diagnostic Radiology and Nuclear Medicine, Trauma and Emergency Radiology (D.D., U.B., A.B., N.T., G.I., E.N., R.C., E.S.) and Department of Orthopedics, Division of Orthopedic Traumatology (J.W.N., L.B., D.M., R.V.O.), University of Maryland Medical Center, R Adams Cowley Shock Trauma Center, 22 S Greene St, Baltimore, MD 21201.

|March 21, 2018

Summary

A CT-based model accurately predicts arterial injury in pelvic disruptions using hematoma volume. This tool aids in identifying patients needing embolization and predicting mortality risk.

More Related Videos

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Published on: November 24, 2016

Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury

Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury

Published on: September 7, 2018

Related Experiment Videos

Last Updated: Feb 13, 2026

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

A Scalable Model to Study the Effects of Blunt-Force Injury in Adult Zebrafish

Published on: May 31, 2021

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Reproducible Arterial Denudation Injury by Infrarenal Abdominal Aortic Clamping in a Murine Model

Published on: November 24, 2016

Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury

Ferric Chloride-induced Canine Carotid Artery Thrombosis: A Large Animal Model of Vascular Injury

Published on: September 7, 2018

Area of Science:

Radiology
Trauma Surgery
Medical Imaging Analysis

Background:

Blunt pelvic ring disruptions can cause severe arterial hemorrhage.
Predicting the need for intervention like transarterial embolization (TAE) is critical.
Existing methods may lack precision in assessing injury severity.

Purpose of the Study:

To develop and validate a computed tomography (CT)-based predictive model for major arterial injury.
To incorporate semiautomated pelvic hematoma volume quantification into the model.
To estimate the probability of arterial injury and associated mortality.

Main Methods:

Developed a multivariable logistic regression model using CT data from patients with blunt pelvic ring disruptions.
Quantified pelvic hematoma volume using semiautomated segmentation.
Validated the model's performance against trauma radiologists using receiver operating characteristic (ROC) analysis.

Main Results:

Key predictors included hematoma volume, contrast extravasation, atherosclerosis, rotational instability, and obturator ring fracture.
The CT-based model demonstrated strong predictive performance (AUC, 0.78), comparable to expert readers.
A hematoma volume cutoff of 433 mL predicted major arterial injury requiring TAE with 87%-100% positive predictive value.

Conclusions:

A CT-derived logistic regression model provides objective probability estimates for major arterial injury.
Pelvic hematoma volume correlates with transfusion requirements and can help predict mortality risk.
The model aids in clinical decision-making for trauma patients with pelvic disruptions.