Related Experiment Video
Updated: Feb 13, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
Published on: October 17, 2018
Acute metabolic responses following different resistance exercise protocols
Samuel Silva Aguiar1, Caio Victor Sousa1, Herbert Gustavo Simões1
1a Graduate Program in Physical Education, Universidade Católica de Brasília, Taguatinga-DF, Brazil.
Resistance exercise improves glycemic control. A moderate intensity (3-4 sets of 9-12 repetitions) appears optimal for acute postprandial glucose management, showing significant reductions in glucose area under the curve.
Area of Science:
- Exercise Physiology
- Metabolic Health
- Sports Science
Background:
- Resistance exercise (RE) is recognized for its benefits in glycemic control.
- Previous studies confirm single RE sessions can lower blood glucose in individuals with and without diabetes.
- The dose-response relationship between RE intensity/volume and glycemic control remains underexplored.
Purpose of the Study:
- To investigate the acute metabolic responses to different resistance exercise protocols.
- To determine the optimal resistance exercise prescription for immediate postprandial glucose regulation.
- To examine the relationship between exercise volume, intensity, and glycemic and lactate responses.
Main Methods:
- Eighty-nine males were randomized into six groups: varying sets/repetitions/intensities of RE or a control.
- Participants completed an oral glucose tolerance test with metabolic monitoring post-exercise.
- Measurements included glucose and lactate area under the curve (AUC) over 120 minutes recovery.
Main Results:
- All resistance exercise groups demonstrated significantly lower glucose AUC compared to the control group.
- The 6 sets of 6 repetitions (6x6 at 90% 1RM) group showed the lowest glucose AUC.
- A significant negative correlation was found between glucose and lactate AUC, suggesting metabolic interplay.
Conclusions:
- Resistance exercise effectively lowers acute postprandial glucose levels.
- A prescription of 3-4 sets with 9-12 repetitions per muscle group may be optimal for glycemic control.
- Further research can refine RE strategies for metabolic health management.
Related Concept Videos
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
What is Metabolism?
Exercise Stress Test
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Responses to Heat and Cold Stress
Resistivity
Resistance

