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Updated: Feb 13, 2026

Organic Solvent-Based Protein Precipitation for Robust Proteome Purification Ahead of Mass Spectrometry
Published on: February 7, 2022
Robustness of anthropogenically forced decadal precipitation changes projected for the 21st century
Honghai Zhang1,2, Thomas L Delworth3
1Program in Atmospheric and Oceanic Sciences, Princeton University, 300 Forrestal Road, Princeton, NJ, 08544, USA. honghaiz@princeton.edu.
Abstract:
Precipitation is characterized by substantial natural variability, including on regional and decadal scales. This relatively large variability poses a grand challenge in assessing the significance of anthropogenically forced precipitation changes. Here we use multiple large ensembles of climate change experiments to evaluate whether, on regional scales, anthropogenic changes in decadal precipitation mean state are distinguishable. Here, distinguishable means the anthropogenic change is outside the range expected from natural variability. Relative to the 1950-1999 period, simulated anthropogenic shifts in precipitation mean state for the 2000-2009 period are already distinguishable over 36-41% of the globe-primarily in high latitudes, eastern subtropical oceans, and the tropics. Anthropogenic forcing in future medium-to-high emission scenarios is projected to cause distinguishable shifts over 68-75% of the globe by 2050 and 86-88% by 2100. Our findings imply anthropogenic shifts in decadal-mean precipitation will exceed the bounds of natural variability over most of the planet within several decades.
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