Related Experiment Video

Updated: Feb 13, 2026

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
09:51

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience

Published on: December 4, 2023

1.7K

Which aortic clamp strategy is better to reduce postoperative stroke and death: Single center report and a

Liyu Chen1, Xiumeng Hua2, Jiangping Song1,2

  • 1Department of Cardiovascular Surgery.

Medicine
|March 22, 2018
PubMed

Insights

Comparing single aortic clamp (SAC) and partial aortic clamp (PAC) strategies for coronary artery bypass grafting (CABG), this study found no significant difference in 30-day stroke or death rates. However, SAC was associated with reduced cardiopulmonary bypass time.

Area of Science:

  • Cardiovascular Surgery
  • Neurosurgery
  • Anesthesiology

Background:

  • Stroke is a significant complication following coronary artery bypass grafting (CABG).
  • Aortic clamping strategies, specifically single aortic clamp (SAC) and partial aortic clamp (PAC), are debated for their impact on postoperative stroke and mortality.
  • This study investigates the comparative efficacy of SAC versus PAC in reducing 30-day postoperative stroke and death.

Purpose of the Study:

  • To compare the incidence of 30-day postoperative stroke between single aortic clamp (SAC) and partial aortic clamp (PAC) strategies in patients undergoing on-pump CABG.
  • To evaluate the 30-day mortality rates associated with SAC versus PAC.
  • To determine if one clamping strategy offers superior outcomes regarding stroke and death.

Main Methods:

  • A single-center retrospective study of 469 patients undergoing on-pump CABG (SAC group: 265 patients, PAC group: 204 patients).
  • A systematic search identified 12 additional studies for meta-analysis.
  • Outcomes assessed included 30-day postoperative stroke and mortality, analyzed using fixed-effect modeling with odds ratios (OR).

Main Results:

  • Patients in the SAC group were older and had higher rates of peripheral vascular disease and hypertension.
  • The SAC group experienced shorter cardiopulmonary bypass times (93.2 ± 22.4 min vs. 103.4 ± 26.8 min).
  • Meta-analysis revealed no significant difference in 30-day postoperative stroke (OR: 0.78, 95% CI: 0.58-1.06) or mortality (OR: 0.82, 95% CI: 0.61-1.10) between SAC and PAC.

Conclusions:

  • Neither single aortic clamp (SAC) nor partial aortic clamp (PAC) strategy demonstrated a significant difference in reducing 30-day postoperative stroke or death.
  • Single aortic clamp (SAC) is associated with a reduced duration of cardiopulmonary bypass.
  • Further research may explore long-term outcomes and specific patient subgroups.
Abstract

More Related Videos

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia04:34

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia

Published on: February 17, 2023

1.7K
A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats06:50

A Model of Acute Lung Injury Following Visceral Ischemia-Reperfusion by Supra-Coeliac Aortic Cross Clamping in Rats

Published on: August 15, 2025

431

Related Concept Videos

Lattice Centering and Coordination Number02:33

Lattice Centering and Coordination Number

The structure of a crystalline solid, whether a metal or not, is best described by considering its simplest repeating unit, which is referred to as its unit cell. The unit cell consists of lattice points that represent the locations of atoms or ions. The entire structure then consists of this unit cell repeating in three dimensions. The three different types of unit cells present in the cubic lattice are illustrated in Figure 1.
Types of Unit Cells
Imagine taking a large number of identical...
12.2K
Directing Effect of Substituents: meta-Directing Groups01:09

Directing Effect of Substituents: meta-Directing Groups

Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
6.0K
Center of Gravity00:58

Center of Gravity

The center of gravity (COG) of an object is the point where the object's total weight is considered to be concentrated. Knowing the location of the center of gravity is useful when predicting the behavior of a moving object or designing static structures. In a uniform gravitational field, the center of gravity is similar to the center of mass (COM); yet, these two points can be positioned differently. For example, the Moon's center of mass lies very close to its geometric center, but...
6.8K
Center of Gravity01:15

Center of Gravity

The center of gravity is the point at which an object's weight appears to be concentrated and can be used to balance the object perfectly. This point is essential in mechanics as it provides information regarding a body's stability and moments of inertia. The center of gravity does not always have to fall within the shape or boundaries of the body; it may also lie outside the body in certain cases.
To determine its location, the principle of moments can be utilized by dividing the object into...
2.2K
Center of Mass00:59

Center of Mass

The center of mass is the point at which the total mass of an object can be said to be concentrated. It is a fundamental principle in mechanics and physics that applies to all objects regardless of their shape or size. The center of gravity is the point at which an object’s weight appears to be concentrated and can be used to balance the object perfectly.
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...
2.1K
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.5K