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Formulation and Characterization of Bioactive Agent Containing Nanodisks
Published on: March 17, 2023
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Bioactive Glasses: Where Are We and Where Are We Going?
Francesco Baino1, Sepideh Hamzehlou2,3, Saeid Kargozar4
1Institute of Materials Physics and Engineering, Applied Science and Technology Department, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy. francesco.baino@polito.it.
Journal of Functional Biomaterials
|March 23, 2018
Summary
Bioactive glasses, like the original 45S5 composition, revolutionize regenerative medicine by bonding to bone and stimulating growth. Ongoing research explores new applications, highlighting the need for interdisciplinary collaboration in biomaterials science.
Area of Science:
- Biomaterials Science
- Regenerative Medicine
- Glass Chemistry
Background:
- Bioactive glasses, pioneered by the 45S5 composition, have transformed healthcare by enabling bone regeneration.
- These materials bond with living tissue and release ions that stimulate osteogenesis.
- Millions of successful patient implants demonstrate their efficacy in bone and dental defect repair.
Purpose of the Study:
- To review current clinical applications of bioactive glasses.
- To identify and discuss six key future challenges in bioactive glass research.
- To encourage interdisciplinary collaboration among researchers and clinicians.
Main Methods:
- Literature review of clinical applications.
- Identification of emerging research challenges.
- Discussion of future research directions and potential applications.
Main Results:
- Bioactive glasses are established in bone and dental defect repair.
- New applications in soft tissue repair and drug delivery are emerging.
- Significant future potential exists for bioactive glass technology.
Conclusions:
- Bioactive glasses represent a cornerstone of modern regenerative medicine.
- Continued innovation requires collaboration between glass chemists, bioengineers, and clinicians.
- Addressing future challenges will unlock the full potential of bioactive glasses in medicine.
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