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Updated: Feb 13, 2026

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
Published on: November 4, 2015
Adiponectin in Chronic Thromboembolic Pulmonary Hypertension
Sarasa Isobe1, Masaharu Kataoka1, Takashi Kawakami1
1Department of Cardiology, Keio University School of Medicine.
Background:
The correlation between serum adiponectin concentration and hemodynamics or certain metabolic markers in patients with chronic thromboembolic pulmonary hypertension (CTEPH) is unknown.
Methods And Results:
We enrolled 30 CTEPH patients who underwent interventional therapy of balloon pulmonary angioplasty or pulmonary endarterectomy. Serum adiponectin concentrations positively correlated with B-type natriuretic peptide (BNP) concentrations, pulmonary vascular resistance, and mean pulmonary arterial pressure. After the therapeutic interventions, serum adiponectin concentrations improved and changes in serum adiponectin concentrations significantly correlated with changes in BNP concentrations.
Conclusions:
Adiponectin can be a useful marker for the severity of CTEPH.
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