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Updated: Feb 13, 2026
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Merkel Cell Carcinoma.
Shravan Shanbhag1, Amol Amonkar1
1Department of Surgery, K.S Hegde Medical Academy, Mangalore, India.
Indian Journal of Surgical Oncology
|March 23, 2018
Summary
Merkel cell carcinoma (MCC), a rare skin cancer, can present as nodules. This case highlights advanced MCC with extensive distant metastases, emphasizing the need for comprehensive staging.
Area of Science:
- Oncology
- Dermatology
- Pathology
Background:
- Merkel cell carcinoma (MCC) is a rare, aggressive neuroendocrine skin cancer.
- It typically affects sun-exposed areas in the elderly.
- Diagnosis can be challenging, often requiring advanced techniques.
Purpose of the Study:
- To report a case of Merkel cell carcinoma with extensive distant metastases.
- To discuss diagnostic and staging challenges.
- To review relevant literature on advanced MCC.
Main Methods:
- Clinical presentation of a 73-year-old male with nodular swellings.
- Biopsy and immunohistochemistry for Merkel cell carcinoma diagnosis.
- Ultrasound and computed tomography (CT) for staging and metastasis assessment.
Main Results:
- Biopsy confirmed Merkel cell carcinoma.
- Imaging revealed extensive lymphadenopathy (para-aortic, retroperitoneal, iliac, inguinal) with necrotic centers.
- CT showed soft tissue nodules, abdominal lymphadenopathy encasing major vessels, and right hydronephrosis.
Conclusions:
- The case demonstrates advanced Merkel cell carcinoma with widespread distant metastases.
- Comprehensive imaging is crucial for accurate staging.
- Early detection and multidisciplinary management are vital for improving outcomes in MCC.
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