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A case report of rapid-onset hyponatremia induced by low-dose olanzapine
Sethulakshmi Sreevalsam Anil1, Badr Ratnakaran2, Nisha Suresh3
1Department of Psychiatry, Government Medical College, Thiruvananthapuram, Kerala, India.
Abstract:
Hyponatremia has been reported with the use of psychotropic drugs. Olanzapine does not find much mention as a cause of hyponatremia in literature; however, it has been found to be the second most frequently reported atypical antipsychotic to cause it. We report a case of hyponatremia due to syndrome of inappropriate antidiuretic hormone secretion which occurred at a rapid onset following the administration of low-dose olanzapine during inpatient treatment of a patient with bipolar disorder. We would like to highlight our case for the need to be vigil about such fatal side complications apart from metabolic side effects of atypical antipsychotics.
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