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Updated: Feb 12, 2026

Simple Continuous Glucose Monitoring in Freely Moving Mice
Published on: February 24, 2023
Optimal Sampling Duration for Continuous Glucose Monitoring to Determine Long-Term Glycemic Control
Tonya D Riddlesworth1, Roy W Beck1, Robin L Gal1
11 Jaeb Center for Health Research , Tampa, Florida.
Objective:
To determine the minimum sample of continuous glucose monitoring (CGM) data needed to accurately reflect 3 months of glycemic control.
Research Design And Methods:
Three months of CGM data were collected on 257 individuals (age 10-78 years) with type 1 diabetes in two studies (one using the Abbott FreeStyle Libre Pro™ and the other using the Dexcom™ G4). Correlations were calculated between the full 3 months and incremental sampling periods of CGM data.
Results:
Correlation to the full 3 months of data improved with an increasing number of days of data collection, plateauing by about 14 days, with an R2 value of 0.84-0.86 for mean glucose, time at 70-180 mg/dL, and time >180 mg/dL, with lower values for time <70 mg/dL (0.76) and coefficient of variation (0.70).
Conclusions:
Fourteen days of CGM data provide a good estimation of glucose metrics for a 3-month period.
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