Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chemical Reactions in Aqueous Solutions03:03

Chemical Reactions in Aqueous Solutions

72.7K
Chemical substances interact in many different ways. Certain chemical reactions exhibit common patterns of reactivity. Due to the vast number of chemical reactions, it becomes necessary to classify them based on the observed patterns of interaction.
72.7K
Aqueous Solutions and Heats of Hydration02:42

Aqueous Solutions and Heats of Hydration

18.1K
Water and other polar molecules are attracted to ions. The electrostatic attraction between an ion and a molecule with a dipole is called an ion-dipole attraction. These attractions play an important role in the dissolution of ionic compounds in water.
When ionic compounds dissolve in water, the ions in the solid separate and disperse uniformly throughout the solution because water molecules surround and solvate the ions, reducing the strong electrostatic forces between them. This process...
18.1K
Light as Energy01:35

Light as Energy

96.3K
The energy required to carry out photosynthesis is light— typically electromagnetic radiation from the sun. The range of all possible wavelengths is known as the electromagnetic spectrum.
Photons
A photon is a discrete electromagnetic particle or bundle of energy. Photons are characterized by their frequency, wavelength, and amplitude, similar to the properties of a wave. Waves with higher frequencies transmit more energy and have shorter wavelengths than longer wavelengths that transmit...
96.3K
Red Algae01:23

Red Algae

1.0K
Red algae, also known as rhodophytes, are primarily found in marine environments, though some species inhabit freshwater and terrestrial ecosystems. These organisms exist in both unicellular and multicellular forms, with some multicellular varieties reaching macroscopic sizes.As phototrophic organisms, red algae contain chlorophyll a; however, their chloroplasts lack chlorophyll b. Instead, they possess phycobiliproteins, which serve as major light-harvesting pigments, similar to those found in...
1.0K
Photoreceptors and Plant Responses to Light02:00

Photoreceptors and Plant Responses to Light

28.6K
Light plays a significant role in regulating the growth and development of plants. In addition to providing energy for photosynthesis, light provides other important cues to regulate a range of developmental and physiological responses in plants.
28.6K
The Wave Nature of Light02:12

The Wave Nature of Light

61.6K
The nature of light has been a subject of inquiry since antiquity. In the seventeenth century, Isaac Newton performed experiments with lenses and prisms and was able to demonstrate that white light consists of the individual colors of the rainbow combined together. Newton explained his optics findings in terms of a "corpuscular" view of light, in which light was composed of streams of extremely tiny particles traveling at high speeds according to Newton's laws of motion.
61.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

AI-driven Chinese male facial skin phenotype profiling and its lifestyle correlation.

Scientific reports·2026
Same author

Can explainable AI scaffolding reduce cognitive load and enhance embodied expression? A quasi-experimental study of multilingual vocal learning in Bel Canto education.

Frontiers in psychology·2026
Same author

Genetic divergence in Aedes aegypti mosquitoes potentially associated with enhanced capacity for arbovirus transmission.

BMC biology·2026
Same author

Corrigendum to "CaWRKY8 participates in the defense response of pepper to pepper mild mottle virus by negatively regulating the expression of defense-related genes" [Plant Sci. 370 (September) (2026) 113227].

Plant science : an international journal of experimental plant biology·2026
Same author

A receptor-Fc based SFV replicon Trim-Away platform for targeted viral protein degradation.

Virology journal·2026
Same author

Comparative analysis of postoperative outcomes and utilization trends for valve-in-valve transcatheter aortic valve implantation versus reoperative surgical aortic valve replacement.

Journal of cardiothoracic surgery·2026

Related Experiment Video

Updated: Feb 12, 2026

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
09:27

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Published on: February 17, 2017

10.8K

Rapid Aqueous Photouncaging by Red Light.

Xiaodi Wang1, Julia A Kalow1

  • 1Department of Chemistry , Northwestern University , Evanston , Illinois 60208 , United States.

Organic Letters
|March 23, 2018
PubMed
Summary

Researchers developed three novel red-photocleavable dyes for uncaging applications. The top dye shows high efficiency and photo-orthogonality, enabling deeper tissue penetration for biological research.

Area of Science:

  • Organic Chemistry
  • Photochemistry
  • Chemical Biology

Background:

  • Photocleavable protecting groups (photolabile groups) are essential tools in chemical biology for spatiotemporal control of molecular release.
  • Red light offers advantages for biological applications due to deeper tissue penetration compared to UV light.
  • Development of efficient red-photocleavable dyes remains a challenge.

Purpose of the Study:

  • To synthesize and characterize novel red-photocleavable dyes.
  • To evaluate the performance of the best dye in terms of quantum yield and uncaging efficiency.
  • To demonstrate photo-orthogonality with UV-activated systems and assess penetration depth in a gel matrix.

Main Methods:

  • Synthesis of three new red-photocleavable dyes.

More Related Videos

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth
11:06

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth

Published on: April 23, 2019

8.3K
A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering
05:18

A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering

Published on: December 7, 2016

10.2K

Related Experiment Videos

Last Updated: Feb 12, 2026

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues
09:27

Rapid One-step Enzymatic Synthesis and All-aqueous Purification of Trehalose Analogues

Published on: February 17, 2017

10.8K
Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth
11:06

Daily Phototherapy with Red Light to Regulate Candida albicans Biofilm Growth

Published on: April 23, 2019

8.3K
A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering
05:18

A Rapid and Chemical-free Hemoglobin Assay with Photothermal Angular Light Scattering

Published on: December 7, 2016

10.2K
  • Photophysical characterization including quantum yield determination.
  • Photocleavage experiments using a 626 nm LED to release benzoic acid.
  • Photo-orthogonality assessment with a UV-activated photolabile group.
  • Qualitative evaluation of dye penetration in a gel.

    • Main Results:

    • Three new red-photocleavable dyes were successfully synthesized.
    • The lead dye demonstrated a quantum yield of 5.7% in a 30:70 water/acetonitrile mixture.
    • Approximately 80% release of benzoic acid was achieved with 626 nm LED irradiation.
    • Photo-orthogonality was confirmed between the red-photocleavable dye and a UV-activated group.
    • The red-photocleavable dye exhibited superior penetration depth in a gel compared to the UV-activated dye.

    Conclusions:

    • The developed red-photocleavable dyes are promising tools for phototriggered molecular release.
    • The best-performing dye offers high efficiency and photo-orthogonality, suitable for biological applications.
    • The superior penetration depth of the red-light activated dye facilitates applications requiring deeper light access, such as in vivo studies.