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Related Experiment Video

Updated: Feb 12, 2026

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
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Resting Heart Rate Is Not Associated with Cognitive Function.

Mette Wod1, Magnus Thorsten Jensen2, Søren Galatius3

  • 1The Unit of Epidemiology, Biostatistics and Biodemography, The Danish Twin Registry, The Danish Aging Research Center, Odense, Denmark.

Neuroepidemiology
|March 23, 2018
PubMed
Summary
This summary is machine-generated.

Elevated resting heart rate (RHR) does not appear to impact cognitive function in the general population. This study found no association between RHR and cognitive scores in middle-aged and elderly Danish individuals.

Keywords:
CardiovascularCognitive functionResting heart rateTwin study

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Area of Science:

  • Cardiology
  • Neuroscience
  • Gerontology

Background:

  • Elevated resting heart rate (RHR) is linked to adverse health outcomes and reduced physical fitness.
  • The relationship between RHR and cognitive function remains an area of investigation, particularly in aging populations.

Purpose of the Study:

  • To investigate the association between resting heart rate (RHR) and cognitive scores in a large cohort of Danish adults.
  • To determine if elevated RHR is indicative of impaired cognitive function across different age groups.

Main Methods:

  • Analysis of cognitive test results from 7,002 Danish individuals (middle-aged, elderly, and nonagenarian).
  • Resting heart rate (RHR) was assessed manually, and cognitive scores were compared using adjusted linear regression models.
  • Twin pair analyses were conducted to control for genetic and environmental factors.

Main Results:

  • No significant association was found between resting heart rate (RHR) and cognitive function in unadjusted or adjusted models.
  • Intrapair analyses within twin pairs also revealed no link between higher RHR and lower cognitive scores.

Conclusions:

  • Resting heart rate (RHR) does not demonstrate a relationship with cognitive function in the general Danish population.
  • Findings suggest that RHR may not be a reliable indicator of cognitive health or decline.