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Updated: Feb 12, 2026

Quantitative Measurement of the Immune Response and Sleep in Drosophila
Published on: December 4, 2012
Sleep, Anesthesia, and Plasticity
Igor Timofeev1, Sylvain Chauvette2
1Department of Psychiatry and Neuroscience, Université Laval, Québec G1V 0A6, Canada; CERVO Brain Research Center, Université Laval, Québec G1J 2G3, Canada.
Abstract:
Two theories continuously clash: does sleep downscale or potentiate synapses? A study in Neuron by González-Rueda et al. (2018) demonstrates overall synaptic depression during anesthesia-induced slow-wave activity. Because anesthesia is typically associated with amnesia, the question of whether slow-wave sleep potentiates or depresses cortical synapses remains open.
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